Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy

Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy

Abstract Background The clinical course of IgA nephropathy (IgAN) is variable and complement activation may predict prognosis. The present study investigated whether glomerular abundance of complement proteins associates with progression to end-stage renal disease (ESRD) in patients for whom prognos...

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Bibliographic Details
Main Authors: Teodora Ioana Flavia Paunas, Kenneth Finne, Sabine Leh, Hans-Peter Marti, Tom Eirik Mollnes, Frode Berven, Bjørn Egil Vikse
Format: Article
Language:English
Published: BioMed Central 2017-08-01
Series:Clinical Proteomics
Subjects:
IgA nephropathy
Complement
ESRD
Formalin-fixed paraffin embedded kidney biopsy tissue
Liquid chromatography–tandem mass spectrometry
Proteomic analyses
Online Access:http://link.springer.com/article/10.1186/s12014-017-9165-x

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http://link.springer.com/article/10.1186/s12014-017-9165-x

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