A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy

A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy

Abstract Background The identification of a DNA variant in pyridoxal kinase (Pdxk) associated with increased risk to Parkinson disease (PD) gene led us to study the inhibition of this gene in the Dopa decarboxylase (Ddc)-expressing neurons of the well-studied model organism Drosophila melanogaster....

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Bibliographic Details
Main Authors: P. Githure M’Angale, Brian E. Staveley
Format: Article
Language:English
Published: BioMed Central 2017-06-01
Series:BMC Research Notes
Subjects:
Dopaminergic neurons
Drosophila
Parkinson disease
Pyridoxal kinase
Pyridoxal 5′ phosphate
Buffy
Online Access:http://link.springer.com/article/10.1186/s13104-017-2526-8

Internet

http://link.springer.com/article/10.1186/s13104-017-2526-8

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