Human Vascular Endothelial Growth Factor A165 Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration

Human Vascular Endothelial Growth Factor A165 Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration

Vascular endothelial growth factor (VEGF) expression induces age-related macular degeneration (AMD), which is a common vision-threatening disease due to choroidal neovascularization and a fibrovascular membrane. We describe a mouse model of neovascular AMD with the local expression of human VEGF-A16...

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Bibliographic Details
Main Authors: Emmi Kokki, Tommi Karttunen, Venla Olsson, Kati Kinnunen, Seppo Ylä-Herttuala
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Genes
Subjects:
adenovirus
age-related macular degeneration
animal model
gene therapy
gene transfer
neovascularization
subretinal
vascular endothelial growth factor
Online Access:http://www.mdpi.com/2073-4425/9/9/438

Internet

http://www.mdpi.com/2073-4425/9/9/438

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