Magnesium sulphate: A Life Saving Drug

  Fever with seizure, a common presentation with which a child may present to the emergency is mainly due to febrile seizure, but it may also be due to meningitis. This study was done to find out the incidence of meningitis and to find out whether lumbar puncture is necessary in different age group...

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Main Authors: Kusum Thapa, R Jha
Format: Article
Language:English
Published: Nepal Medical Association 2008-07-01
Series:Journal of Nepal Medical Association
Online Access:http://jnma.com.np/jnma/index.php/jnma/article/view/300
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spelling doaj-art-4cbc5b0525d2412fbdce5b36d0a90ad22018-09-01T09:30:12ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2008-07-014717110.31729/jnma.300Magnesium sulphate: A Life Saving DrugKusum Thapa0R Jha1Paropakar Maternity and Women’s Hospital Thapathali, Kathmandu, NepalTribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal   Fever with seizure, a common presentation with which a child may present to the emergency is mainly due to febrile seizure, but it may also be due to meningitis. This study was done to find out the incidence of meningitis and to find out whether lumbar puncture is necessary in different age groups of children presenting with first episode of fever with seizure. A prospective study was conducted in the emergency department of Kanti Children's Hospital. Children who presented with first episode of fever and seizure in the age group of 6 months to 5 years were included. Meningitis was diagnosed on the basis of either cytological and biochemical criteria or if a bacterial pathogen was isolated. Of the 175 children included, 17% were diagnosed to have meningitis. Cerebrospinal fluid was positive for a bacterial pathogen in 4.5% of the cases. In the age group of 6 months to 12 months, 30% of the children had meningitis as compared to 20 % and 5% in other age groups of 12- 18 months and above 18 months respectively. All children with culture proven bacterial meningitis were in the age group of 6-12 months and had no evidence of meningeal irritation. Signs of meningeal irritation had high specificity in diagnosing meningitis. Organisms grown were Haemophilus influenza in three cases, Streptococcus pneumoniae in two cases and Staphylococcus aureus in three cases. In conclusion, incidence of meningitis was found to be high in children presenting with first episode of fever and seizure. Lumbar puncture to rule out meningitis should especially be considered in children in the younger age group even without evidence of meningeal irritation.http://jnma.com.np/jnma/index.php/jnma/article/view/300
institution Open Data Bank
collection Open Access Journals
building Directory of Open Access Journals
language English
format Article
author Kusum Thapa
R Jha
spellingShingle Kusum Thapa
R Jha
Magnesium sulphate: A Life Saving Drug
Journal of Nepal Medical Association
author_facet Kusum Thapa
R Jha
author_sort Kusum Thapa
title Magnesium sulphate: A Life Saving Drug
title_short Magnesium sulphate: A Life Saving Drug
title_full Magnesium sulphate: A Life Saving Drug
title_fullStr Magnesium sulphate: A Life Saving Drug
title_full_unstemmed Magnesium sulphate: A Life Saving Drug
title_sort magnesium sulphate: a life saving drug
publisher Nepal Medical Association
series Journal of Nepal Medical Association
issn 0028-2715
1815-672X
publishDate 2008-07-01
description   Fever with seizure, a common presentation with which a child may present to the emergency is mainly due to febrile seizure, but it may also be due to meningitis. This study was done to find out the incidence of meningitis and to find out whether lumbar puncture is necessary in different age groups of children presenting with first episode of fever with seizure. A prospective study was conducted in the emergency department of Kanti Children's Hospital. Children who presented with first episode of fever and seizure in the age group of 6 months to 5 years were included. Meningitis was diagnosed on the basis of either cytological and biochemical criteria or if a bacterial pathogen was isolated. Of the 175 children included, 17% were diagnosed to have meningitis. Cerebrospinal fluid was positive for a bacterial pathogen in 4.5% of the cases. In the age group of 6 months to 12 months, 30% of the children had meningitis as compared to 20 % and 5% in other age groups of 12- 18 months and above 18 months respectively. All children with culture proven bacterial meningitis were in the age group of 6-12 months and had no evidence of meningeal irritation. Signs of meningeal irritation had high specificity in diagnosing meningitis. Organisms grown were Haemophilus influenza in three cases, Streptococcus pneumoniae in two cases and Staphylococcus aureus in three cases. In conclusion, incidence of meningitis was found to be high in children presenting with first episode of fever and seizure. Lumbar puncture to rule out meningitis should especially be considered in children in the younger age group even without evidence of meningeal irritation.
url http://jnma.com.np/jnma/index.php/jnma/article/view/300
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