H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia

Abstract Background The long non-coding RNA H19 plays a crucial role in solid tumor initiation and progression. However, the potential role of H19 and its clinical significance in acute myeloid leukemia (AML) remain largely elusive. Methods H19 expression was detected by qPCR, and clinical significa...

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Bibliographic Details
Main Authors: Ting-juan Zhang, Jing-dong Zhou, Wei Zhang, Jiang Lin, Ji-chun Ma, Xiang-mei Wen, Qian Yuan, Xi-xi Li, Zi-jun Xu, Jun Qian
Format: Article
Language:English
Published: BioMed Central 2018-04-01
Series:Clinical Epigenetics
Subjects:
H19
ID2
AML
Online Access:http://link.springer.com/article/10.1186/s13148-018-0486-z