FDHE-IW: A Fast Approach for Detecting High-Order Epistasis in Genome-Wide Case-Control Studies

Detecting high-order epistasis in genome-wide association studies (GWASs) is of importance when characterizing complex human diseases. However, the enormous numbers of possible single-nucleotide polymorphism (SNP) combinations and the diversity among diseases presents a significant computational cha...

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Bibliographic Details
Main Author: Shouheng Tuo
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/9/9/435