NLRP3 and CARD8 Polymorphisms Influence Higher Disease Activity in Rheumatoid Arthritis

NLRP3 and CARD8 Polymorphisms Influence Higher Disease Activity in Rheumatoid Arthritis

Background: The activation of NLRP3-inflammasome may contribute to inflammatory processes in rheumatoid arthritis (RA). Functional polymorphisms in the genes coding for its components NLRP3 and CARD8 were associated with a proinflammatory phenotype. Our aim was to investigate the influence of these...

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Bibliographic Details
Main Authors: Jenko Barbara, Praprotnik Sonja, Tomšić Matija, Dolžan Vita
Format: Article
Language:English
Published: Sciendo 2016-09-01
Series:Journal of Medical Biochemistry
Subjects:
polymorphism
rheumatoid arthritis
inflammasome
BIRC5
NLRP3
Online Access:http://www.degruyter.com/view/j/jomb.2016.35.issue-3/jomb-2016-0008/jomb-2016-0008.xml?format=INT

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http://www.degruyter.com/view/j/jomb.2016.35.issue-3/jomb-2016-0008/jomb-2016-0008.xml?format=INT

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