HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequencing

Abstract Background The ability to accurately and efficiently measure DNA methylation is critical to advance the understanding of this epigenetic mechanism and its contribution to common diseases. Here, we present a highly accurate method to measure methylation using bisulfite sequencing (termed HAM...

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Bibliographic Details
Main Authors: Simone Roeh, Tobias Wiechmann, Susann Sauer, Maik Ködel, Elisabeth B. Binder, Nadine Provençal
Format: Article
Language:English
Published: BioMed Central 2018-07-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-018-0209-x