Platelet activation and prothrombotic properties in a mouse model of peritoneal sepsis

Abstract Sepsis is associated with thrombocytopenia and microvascular thrombosis. Studies have described platelets implication in this pathology but their kinetics of activation and behavior remain poorly known. We show in a mouse model of peritonitis, the appearance of platelet-rich thrombi in orga...

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Bibliographic Details
Main Authors: Fanny Vardon Bounes, Vincent Mémier, Marina Marcaud, Aemilia Jacquemin, Hind Hamzeh-Cognasse, Cédric Garcia, Jennifer Series, Pierre Sié, Vincent Minville, Marie-Pierre Gratacap, Bernard Payrastre
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Scientific Reports
Online Access:http://link.springer.com/article/10.1038/s41598-018-31910-8