Impact of partial volume correction on the regional correspondence between in vivo [C-11]PiB PET and postmortem measures of Aβ load

Impact of partial volume correction on the regional correspondence between in vivo [C-11]PiB PET and postmortem measures of Aβ load

The positron emission tomography (PET) radiotracer Pittsburgh Compound B ([C-11]PiB) demonstrates a high affinity for fibrillary amyloid-beta (Aβ) aggregates. However, [C-11]PiB's in vivo sensitivity and specificity is an ongoing area of investigation in correlation studies with postmortem meas...

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Bibliographic Details
Main Authors: Davneet S. Minhas, Julie C. Price, Charles M. Laymon, Carl R. Becker, William E. Klunk, Dana L. Tudorascu, Eric E. Abrahamson, Ronald L. Hamilton, Julia K. Kofler, Chester A. Mathis, Oscar L. Lopez, Milos D. Ikonomovic
Format: Article
Language:English
Published: Elsevier
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158218301165

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