Chickens Expressing IFIT5 Ameliorate Clinical Outcome and Pathology of Highly Pathogenic Avian Influenza and Velogenic Newcastle Disease Viruses

Chickens Expressing IFIT5 Ameliorate Clinical Outcome and Pathology of Highly Pathogenic Avian Influenza and Velogenic Newcastle Disease Viruses

Innate antiviral immunity establishes first line of defense against invading pathogens through sensing their molecular structures such as viral RNA. This antiviral potential of innate immunity is mainly attributed to a myriad of IFN-stimulated genes (ISGs). Amongst well-characterized ISGs, we have p...

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Bibliographic Details
Main Authors: Mohammed A. Rohaim, Diwakar Santhakumar, Rania F. El Naggar, Munir Iqbal, Hussein A. Hussein, Muhammad Munir
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
innate immunity
antiviral response
transgenic
viruses
host registance
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02025/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02025/full

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