Anti-IgE therapy for IgE-mediated allergic diseases: from neutralizing IgE antibodies to eliminating IgE+ B cells
Abstract Allergic diseases are inflammatory disorders that involve many types of cells and factors, including allergens, immunoglobulin (Ig)E, mast cells, basophils, cytokines and soluble mediators. Among them, IgE plays a vital role in the development of acute allergic reactions and chronic inflamm...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2018-07-01
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Series: | Clinical and Translational Allergy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13601-018-0213-z |