Anti-IgE therapy for IgE-mediated allergic diseases: from neutralizing IgE antibodies to eliminating IgE+ B cells

Abstract Allergic diseases are inflammatory disorders that involve many types of cells and factors, including allergens, immunoglobulin (Ig)E, mast cells, basophils, cytokines and soluble mediators. Among them, IgE plays a vital role in the development of acute allergic reactions and chronic inflamm...

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Bibliographic Details
Main Authors: Jiayun Hu, Jiajie Chen, Lanlan Ye, Zelang Cai, Jinlu Sun, Kunmei Ji
Format: Article
Language:English
Published: BioMed Central 2018-07-01
Series:Clinical and Translational Allergy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13601-018-0213-z