Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity

Spread hepatic tumours are not suitable for treatment either by surgery or conventional ablation methods. The aim of this study was to evaluate feasibility and safety of selectively increasing the healthy hepatic conductivity by the hypersaline infusion (HI) through the portal vein. We hypothesize t...

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Main Authors: Pañella Clara, Castellví Quim, Moll Xavier, Quesada Rita, Villanueva Alberto, Iglesias Mar, Naranjo Dolores, Sánchez-Velázquez Patricia, Andaluz Anna, Grande Luís, Ivorra Antoni, Burdío Fernando
Format: Article
Language:English
Published: Sciendo 2017-11-01
Series:Radiology and Oncology
Subjects:
Online Access:http://www.degruyter.com/view/j/raon.2017.51.issue-4/raon-2017-0051/raon-2017-0051.xml?format=INT
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spelling doaj-art-341718bbd03a4c2d866dda9e4752fe632018-09-02T17:59:12ZengSciendoRadiology and Oncology1581-32072017-11-0151441542110.1515/raon-2017-0051raon-2017-0051Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivityPañella Clara0Castellví Quim1Moll Xavier2Quesada Rita3Villanueva Alberto4Iglesias Mar5Naranjo Dolores6Sánchez-Velázquez Patricia7Andaluz Anna8Grande Luís9Ivorra Antoni10Burdío Fernando11General Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainDepartment of Informatics and Communication Technologies, Universitat Pompeu Fabra, Barcelona, SpainDepartment of Pathological Anatomy, Hospital del Mar Medical Research Insitute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainGeneral Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainChemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, SpainMedical and Surgery Animal Department, Faculty of Veterinary, Universitat Autònoma de Barcelona, Cerdanyola del VallèsBarcelona, SpainMedical and Surgery Animal Department, Faculty of Veterinary, Universitat Autònoma de Barcelona, Cerdanyola del VallèsBarcelona, SpainGeneral Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainDepartment of Pathological Anatomy, Hospital del Mar Medical Research Insitute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainGeneral Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainDepartment of Informatics and Communication Technologies, Universitat Pompeu Fabra, Barcelona, SpainGeneral Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainSpread hepatic tumours are not suitable for treatment either by surgery or conventional ablation methods. The aim of this study was to evaluate feasibility and safety of selectively increasing the healthy hepatic conductivity by the hypersaline infusion (HI) through the portal vein. We hypothesize this will allow simultaneous safe treatment of all nodules by irreversible electroporation (IRE) when applied in a transhepatic fashion.http://www.degruyter.com/view/j/raon.2017.51.issue-4/raon-2017-0051/raon-2017-0051.xml?format=INTirreversible electroporationliver tumourelectrical conductivity
institution Open Data Bank
collection Open Access Journals
building Directory of Open Access Journals
language English
format Article
author Pañella Clara
Castellví Quim
Moll Xavier
Quesada Rita
Villanueva Alberto
Iglesias Mar
Naranjo Dolores
Sánchez-Velázquez Patricia
Andaluz Anna
Grande Luís
Ivorra Antoni
Burdío Fernando
spellingShingle Pañella Clara
Castellví Quim
Moll Xavier
Quesada Rita
Villanueva Alberto
Iglesias Mar
Naranjo Dolores
Sánchez-Velázquez Patricia
Andaluz Anna
Grande Luís
Ivorra Antoni
Burdío Fernando
Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity
Radiology and Oncology
irreversible electroporation
liver tumour
electrical conductivity
author_facet Pañella Clara
Castellví Quim
Moll Xavier
Quesada Rita
Villanueva Alberto
Iglesias Mar
Naranjo Dolores
Sánchez-Velázquez Patricia
Andaluz Anna
Grande Luís
Ivorra Antoni
Burdío Fernando
author_sort Pañella Clara
title Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity
title_short Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity
title_full Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity
title_fullStr Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity
title_full_unstemmed Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity
title_sort focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. preliminary results on differential conductivity
publisher Sciendo
series Radiology and Oncology
issn 1581-3207
publishDate 2017-11-01
description Spread hepatic tumours are not suitable for treatment either by surgery or conventional ablation methods. The aim of this study was to evaluate feasibility and safety of selectively increasing the healthy hepatic conductivity by the hypersaline infusion (HI) through the portal vein. We hypothesize this will allow simultaneous safe treatment of all nodules by irreversible electroporation (IRE) when applied in a transhepatic fashion.
topic irreversible electroporation
liver tumour
electrical conductivity
url http://www.degruyter.com/view/j/raon.2017.51.issue-4/raon-2017-0051/raon-2017-0051.xml?format=INT
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