Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity
Spread hepatic tumours are not suitable for treatment either by surgery or conventional ablation methods. The aim of this study was to evaluate feasibility and safety of selectively increasing the healthy hepatic conductivity by the hypersaline infusion (HI) through the portal vein. We hypothesize t...
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Series: | Radiology and Oncology |
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doaj-art-341718bbd03a4c2d866dda9e4752fe632018-09-02T17:59:12ZengSciendoRadiology and Oncology1581-32072017-11-0151441542110.1515/raon-2017-0051raon-2017-0051Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivityPañella Clara0Castellví Quim1Moll Xavier2Quesada Rita3Villanueva Alberto4Iglesias Mar5Naranjo Dolores6Sánchez-Velázquez Patricia7Andaluz Anna8Grande Luís9Ivorra Antoni10Burdío Fernando11General Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainDepartment of Informatics and Communication Technologies, Universitat Pompeu Fabra, Barcelona, SpainDepartment of Pathological Anatomy, Hospital del Mar Medical Research Insitute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainGeneral Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainChemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, SpainMedical and Surgery Animal Department, Faculty of Veterinary, Universitat Autònoma de Barcelona, Cerdanyola del VallèsBarcelona, SpainMedical and Surgery Animal Department, Faculty of Veterinary, Universitat Autònoma de Barcelona, Cerdanyola del VallèsBarcelona, SpainGeneral Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainDepartment of Pathological Anatomy, Hospital del Mar Medical Research Insitute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainGeneral Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainDepartment of Informatics and Communication Technologies, Universitat Pompeu Fabra, Barcelona, SpainGeneral Surgery Department, Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra, Barcelona, SpainSpread hepatic tumours are not suitable for treatment either by surgery or conventional ablation methods. The aim of this study was to evaluate feasibility and safety of selectively increasing the healthy hepatic conductivity by the hypersaline infusion (HI) through the portal vein. We hypothesize this will allow simultaneous safe treatment of all nodules by irreversible electroporation (IRE) when applied in a transhepatic fashion.http://www.degruyter.com/view/j/raon.2017.51.issue-4/raon-2017-0051/raon-2017-0051.xml?format=INTirreversible electroporationliver tumourelectrical conductivity |
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English |
format |
Article |
author |
Pañella Clara Castellví Quim Moll Xavier Quesada Rita Villanueva Alberto Iglesias Mar Naranjo Dolores Sánchez-Velázquez Patricia Andaluz Anna Grande Luís Ivorra Antoni Burdío Fernando |
spellingShingle |
Pañella Clara Castellví Quim Moll Xavier Quesada Rita Villanueva Alberto Iglesias Mar Naranjo Dolores Sánchez-Velázquez Patricia Andaluz Anna Grande Luís Ivorra Antoni Burdío Fernando Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity Radiology and Oncology irreversible electroporation liver tumour electrical conductivity |
author_facet |
Pañella Clara Castellví Quim Moll Xavier Quesada Rita Villanueva Alberto Iglesias Mar Naranjo Dolores Sánchez-Velázquez Patricia Andaluz Anna Grande Luís Ivorra Antoni Burdío Fernando |
author_sort |
Pañella Clara |
title |
Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity |
title_short |
Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity |
title_full |
Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity |
title_fullStr |
Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity |
title_full_unstemmed |
Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity |
title_sort |
focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. preliminary results on differential conductivity |
publisher |
Sciendo |
series |
Radiology and Oncology |
issn |
1581-3207 |
publishDate |
2017-11-01 |
description |
Spread hepatic tumours are not suitable for treatment either by surgery or conventional ablation methods. The aim of this study was to evaluate feasibility and safety of selectively increasing the healthy hepatic conductivity by the hypersaline infusion (HI) through the portal vein. We hypothesize this will allow simultaneous safe treatment of all nodules by irreversible electroporation (IRE) when applied in a transhepatic fashion. |
topic |
irreversible electroporation liver tumour electrical conductivity |
url |
http://www.degruyter.com/view/j/raon.2017.51.issue-4/raon-2017-0051/raon-2017-0051.xml?format=INT |
_version_ |
1612632085024997376 |