GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

Summary: Hypertrophic white adipose tissue (WAT) represents a maladaptive mechanism linked to the risk for developing type 2 diabetes in humans. However, the molecular events that predispose WAT to hypertrophy are poorly defined. Here, we demonstrate that adipocyte hypertrophy is triggered by loss o...

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Bibliographic Details
Main Authors: Karima Drareni, Raphaëlle Ballaire, Serena Barilla, Mano J. Mathew, Amine Toubal, Rongrong Fan, Ning Liang, Catherine Chollet, Zhiqiang Huang, Maria Kondili, Fabienne Foufelle, Antoine Soprani, Ronan Roussel, Jean-François Gautier, Fawaz Alzaid, Eckardt Treuter, Nicolas Venteclef
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718313032

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http://www.sciencedirect.com/science/article/pii/S2211124718313032

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