Metabonomic Profiling Reveals Difference in Altered Metabolic Pathways Between Chronic Kidney Disease and High-Fat-Induced Insulin Resistance in Rats

Background/Aims: Chronic kidney disease (CKD) is closely correlated with the development of insulin resistance (IR). Until now, the underlying molecular mechanisms remain to be elucidated. This study aimed to identify metabolites and molecular pathways unique to CKD-induced IR. Methods: Ultra-perfor...

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Bibliographic Details
Main Authors: Zhuo Xu, Li Zhang, Jiao Li, Yang Zhao, Xiangmei Chen
Format: Article
Language:English
Published: Karger Publishers 2018-08-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:https://www.karger.com/Article/FullText/492247