Telmisartan induces osteosarcoma cells growth inhibition and apoptosis via suppressing mTOR pathway

Telmisartan induces osteosarcoma cells growth inhibition and apoptosis via suppressing mTOR pathway

Osteosarcoma (OS) is a commonly occurring primary malignant bone cancer with serious impact and high mortality, yet effective and safe therapy method not available. The aim of the present study was to elucidate the antitumor effect of telmisartan on human osteosarcoma cells in vitro and its underlyi...

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Bibliographic Details
Main Authors: Wang Chao, Wang Wen-Bo
Format: Article
Language:English
Published: De Gruyter 2018-07-01
Series:Open Life Sciences
Subjects:
Telmisartan
osteosarcoma
mTOR signaling
proliferation
apoptosis
Online Access:http://www.degruyter.com/view/j/biol.2018.13.issue-1/biol-2018-0029/biol-2018-0029.xml?format=INT

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