Listeriolysin o is strongly immunogenic independently of its cytotoxic activity.
The presentation of microbial protein antigens by Major Histocompatibility Complex (MHC) molecules is essential for the development of acquired immunity to infections. However, most biochemical studies of antigen processing and presentation deal with a few relatively inert non-microbial model antige...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3293810?pdf=render |