Endothelial progenitor cells transplantation attenuated blood-brain barrier damage after ischemia in diabetic mice via HIF-1α

Endothelial progenitor cells transplantation attenuated blood-brain barrier damage after ischemia in diabetic mice via HIF-1α

Abstract Background Blood-brain barrier impairment is a major indicator of endothelial dysfunction in diabetes. Studies showed that endothelial progenitor cell (EPC) transplantation promoted angiogenesis and improved function recovery after hind limb ischemia in diabetic mice. The effect of EPC tran...

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Bibliographic Details
Main Authors: Jieli Geng, Liping Wang, Meijie Qu, Yaying Song, Xiaojie Lin, Yajing Chen, Muyassar Mamtilahun, Shengdi Chen, Zhijun Zhang, Yongting Wang, Guo-Yuan Yang
Format: Article
Language:English
Published: BioMed Central 2017-07-01
Series:Stem Cell Research & Therapy
Subjects:
Blood-brain barrier
Diabetes
Endothelial progenitor cell
HIF-1α
Ischemic stroke
Online Access:http://link.springer.com/article/10.1186/s13287-017-0605-3

Internet

http://link.springer.com/article/10.1186/s13287-017-0605-3

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