A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'
The use of citrate to anticoagulate the Continuous Renal Replacement Therapy (CRRT) circuit has not been widely adopted in Australia as an alternative to heparin due to treatment complexity and risks of metabolic complications and availability of suitable solutions. However, interest persists in cit...
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curtin-20.500.11937-79162018-08-08T04:56:12Z A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol' Davies, Hugh Morgan, D. Leslie, Gavin Continuous veno-venous haemodiafiltration Modified Alabama Protocol Regional citrate anticoagulation The use of citrate to anticoagulate the Continuous Renal Replacement Therapy (CRRT) circuit has not been widely adopted in Australia as an alternative to heparin due to treatment complexity and risks of metabolic complications and availability of suitable solutions. However, interest persists in citrate anticoagulation as a viable alternative when heparin is either contraindicated or has failed to provide an adequate circuit lifespan due to dialyser clotting.This paper describes a practical protocol for the delivery of regional citrate anticoagulation for pre-dilutional CVVHDf. The protocol maintains the flexibility in dialysis/ haemofiltration dose prescription and advises on the requirement for monitoring and necessary adjustments to prevent the development of metabolic disturbances. This may assist regional citrate to achieve wider acceptance as an alternative anticoagulation strategy for critically ill patients. 2008 Journal Article http://hdl.handle.net/20.500.11937/7916 10.1016/j.aucc.2008.04.002 Elsevier Inc restricted |
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Curtin University Malaysia |
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Curtin Institutional Repository |
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topic |
Continuous veno-venous haemodiafiltration Modified Alabama Protocol Regional citrate anticoagulation |
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Continuous veno-venous haemodiafiltration Modified Alabama Protocol Regional citrate anticoagulation Davies, Hugh Morgan, D. Leslie, Gavin A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol' |
description |
The use of citrate to anticoagulate the Continuous Renal Replacement Therapy (CRRT) circuit has not been widely adopted in Australia as an alternative to heparin due to treatment complexity and risks of metabolic complications and availability of suitable solutions. However, interest persists in citrate anticoagulation as a viable alternative when heparin is either contraindicated or has failed to provide an adequate circuit lifespan due to dialyser clotting.This paper describes a practical protocol for the delivery of regional citrate anticoagulation for pre-dilutional CVVHDf. The protocol maintains the flexibility in dialysis/ haemofiltration dose prescription and advises on the requirement for monitoring and necessary adjustments to prevent the development of metabolic disturbances. This may assist regional citrate to achieve wider acceptance as an alternative anticoagulation strategy for critically ill patients. |
format |
Journal Article |
author |
Davies, Hugh Morgan, D. Leslie, Gavin |
author_facet |
Davies, Hugh Morgan, D. Leslie, Gavin |
author_sort |
Davies, Hugh |
title |
A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol' |
title_short |
A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol' |
title_full |
A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol' |
title_fullStr |
A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol' |
title_full_unstemmed |
A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol' |
title_sort |
regional citrate anticoagulation protocol for pre-dilutional cvvhdf: the 'modified alabama protocol' |
publisher |
Elsevier Inc |
publishDate |
2008 |
url |
http://hdl.handle.net/20.500.11937/7916 |
first_indexed |
2018-09-06T18:21:30Z |
last_indexed |
2018-09-06T18:21:30Z |
_version_ |
1610883363183263744 |