A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'

The use of citrate to anticoagulate the Continuous Renal Replacement Therapy (CRRT) circuit has not been widely adopted in Australia as an alternative to heparin due to treatment complexity and risks of metabolic complications and availability of suitable solutions. However, interest persists in cit...

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Main Authors: Davies, Hugh, Morgan, D., Leslie, Gavin
Format: Journal Article
Published: Elsevier Inc 2008
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/7916
id curtin-20.500.11937-7916
recordtype eprints
spelling curtin-20.500.11937-79162018-08-08T04:56:12Z A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol' Davies, Hugh Morgan, D. Leslie, Gavin Continuous veno-venous haemodiafiltration Modified Alabama Protocol Regional citrate anticoagulation The use of citrate to anticoagulate the Continuous Renal Replacement Therapy (CRRT) circuit has not been widely adopted in Australia as an alternative to heparin due to treatment complexity and risks of metabolic complications and availability of suitable solutions. However, interest persists in citrate anticoagulation as a viable alternative when heparin is either contraindicated or has failed to provide an adequate circuit lifespan due to dialyser clotting.This paper describes a practical protocol for the delivery of regional citrate anticoagulation for pre-dilutional CVVHDf. The protocol maintains the flexibility in dialysis/ haemofiltration dose prescription and advises on the requirement for monitoring and necessary adjustments to prevent the development of metabolic disturbances. This may assist regional citrate to achieve wider acceptance as an alternative anticoagulation strategy for critically ill patients. 2008 Journal Article http://hdl.handle.net/20.500.11937/7916 10.1016/j.aucc.2008.04.002 Elsevier Inc restricted
repository_type Digital Repository
institution_category Local University
institution Curtin University Malaysia
building Curtin Institutional Repository
collection Online Access
topic Continuous veno-venous haemodiafiltration
Modified Alabama Protocol
Regional citrate anticoagulation
spellingShingle Continuous veno-venous haemodiafiltration
Modified Alabama Protocol
Regional citrate anticoagulation
Davies, Hugh
Morgan, D.
Leslie, Gavin
A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'
description The use of citrate to anticoagulate the Continuous Renal Replacement Therapy (CRRT) circuit has not been widely adopted in Australia as an alternative to heparin due to treatment complexity and risks of metabolic complications and availability of suitable solutions. However, interest persists in citrate anticoagulation as a viable alternative when heparin is either contraindicated or has failed to provide an adequate circuit lifespan due to dialyser clotting.This paper describes a practical protocol for the delivery of regional citrate anticoagulation for pre-dilutional CVVHDf. The protocol maintains the flexibility in dialysis/ haemofiltration dose prescription and advises on the requirement for monitoring and necessary adjustments to prevent the development of metabolic disturbances. This may assist regional citrate to achieve wider acceptance as an alternative anticoagulation strategy for critically ill patients.
format Journal Article
author Davies, Hugh
Morgan, D.
Leslie, Gavin
author_facet Davies, Hugh
Morgan, D.
Leslie, Gavin
author_sort Davies, Hugh
title A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'
title_short A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'
title_full A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'
title_fullStr A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'
title_full_unstemmed A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'
title_sort regional citrate anticoagulation protocol for pre-dilutional cvvhdf: the 'modified alabama protocol'
publisher Elsevier Inc
publishDate 2008
url http://hdl.handle.net/20.500.11937/7916
first_indexed 2018-09-06T18:21:30Z
last_indexed 2018-09-06T18:21:30Z
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