Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

Frequent activation of phosphatidylinositol-3 kinases (PI3K)/Akt/mTOR signaling pathway in gastric cancer (GC) is gaining immense popularity with identification of mutations and/or amplifications of PIK3CA gene or loss of function of PTEN, a tumor suppressor protein, to name a few; both playing a cr...

Full description

Bibliographic Details
Main Authors: Singh, S., Yap, W., Arfuso, Frank, Kar, S., Wang, C., Cai, W., Dharmarajan, Arunasalam, Sethi, Gautam, Kumar, Alan Prem
Format: Journal Article
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/4754

Internet

http://hdl.handle.net/20.500.11937/4754

Similar Items