Pharmacokinetically modified human serum albumin based therapeutic design and development
Human serum albumin (HSA) is synthesized predominantly in the liver, and has an extraordinarily long circulatory half-life (~19 days). Since HSA is responsible for 80% of the colloidal osmotic pressure of plasma, the patients with hypoalbuminemia are typically given a plasma expander to increase the...
Main Authors: | , , , |
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Format: | Book Chapter |
Published: |
2015
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Online Access: | http://hdl.handle.net/20.500.11937/46904 |