Identification of Inhibitor Binding Site in Human Sirtuin 2 Using Molecular Docking and Dynamics Simulations
The ability to identify the site of a protein that can bind with high affinity to small, drug-like compounds has been an important goal in drug design. Sirtuin 2 (SIRT2), histone deacetylase protein family, plays a central role in the regulation of various pathways. Hence, identification of drug for...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal Article |
| Published: |
PLOS
2013
|
| Online Access: | http://hdl.handle.net/20.500.11937/33925 |