Mechanisms of PEDF-mediated protection against reactive oxygen species damage in diabetic retinopathy and neuropathy

Pigment epithelium-derived factor (PEDF) is a pluripotent glycoprotein belonging to the serpin family. PEDF can stimulate several physiological processes such as angiogenesis, cell proliferation and survival. Oxidative stress plays an important role in the occurrence of diabetic retinopathy (DR) whi...

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Bibliographic Details
Main Authors: Elahy, M., Baindur-Hudson, S., Newsholme, Philip, Dass, Crispin
Format: Journal Article
Published: BioScientifica 2014
Online Access:http://hdl.handle.net/20.500.11937/33783