3-phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer

It should be noted that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is a protein encoded by the PDPK1 gene, which plays a key role in the signaling pathways activated by several growth factors and hormones. PDK1 is a crucial kinase that functions downstream of phosphoinositide 3-kinase acti...

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Bibliographic Details
Main Authors: Fyffe, C., Falasca, Marco
Format: Journal Article
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/30988