Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal

Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal

Background: Low bone mineral density (BMD) is a primary risk factor for osteoporosis and is a highly heritable trait, but appears to be influenced by many genes. Genome-wide linkage studies have highlighted the chromosomal region 3p14-p22 as a quantitative trait locus for BMD (LOD 1.1 - 3.5). The FL...

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Bibliographic Details
Main Authors: Mullin, B., Mamotte, Cyril, Prince, R., Spector, T., Dudbridge, F., Wilson, S.
Format: Journal Article
Published: PubMed 2013
Subjects:
Filamin B
Bone mineral density
SNP
Osteoporosis
Online Access:http://hdl.handle.net/20.500.11937/30799

Internet

http://hdl.handle.net/20.500.11937/30799

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