Bp44mT: An orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy
Background and Purpose: Our previous studies demonstrated that a thiosemicarbazone iron chelator (di-2-pyridylketone-4,4-dimethyl-3- thiosemicarbazone; Dp44mT) possesses potent and selective anti-cancer activity but led to cardiotoxicity at non-optimal doses. In this study, we examined the in vivo a...
| Main Authors: | , , |
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| Format: | Journal Article |
| Published: |
John Wiley & Sons
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/27734 |