Compositional and Material Properties of Rat Bone after Bisphosphonate and/or Strontium Ranelate Drug Treatment

PURPOSE: We investigated elemental strontium and/or bisphosphonate drug incorporation upon the compositional and biomechanical properties of vertebral bone, in a rat model of Osteoporosis secondary to ovariectomy. METHODS: Six month old female rats were ovariectomized (OVX) and divided into untrea...

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Bibliographic Details
Main Authors: Wu, Y., Adeeb, S., Duke, M., Munoz-Paniagua, D., Doschak, Michael
Format: Journal Article
Published: Canadian Society for Pharmaceutical Sciences 2013
Online Access:http://ejournals.library.ualberta.ca/index.php/JPPS/article/view/16992/14634
http://hdl.handle.net/20.500.11937/24285