An advanced microencapsulated system: a platform for optimized oral delivery of antidiabetic drug-bile acid formulations

In previous studies, we have shown that a gliclazide-cholic acid derivative (G-CA) mixture resulted in an enhanced ileal permeation of G (ex vivo). When administered orally to diabetic rats, it brought about a significant hypoglycaemic effect. In this study, we aim to create a novel microencapsulate...

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Bibliographic Details
Main Authors: Mooranian, A., Negrulj, R., Mathavan, S., Martinez, J., Sciarretta, J., Chen-Tan, N., Mukkur, T., Mikov, M., Lalic-Popovic, M., Stojancevic, M., Golocorbin-Kon, S., Al-Salami, Hani
Format: Journal Article
Published: TAYLOR & FRANCIS LTD 2015
Online Access:http://hdl.handle.net/20.500.11937/23183