Doxorubicin action on mitochondria: relevance to osteosarcoma therapy?

The mitochondria may very well determine the final commitment of the cell to death, particularly in times of energy stress. Cancer chemotherapeutics such as the anthracycline doxorubicin perturb mitochondrial structure and function in tumour cells, as evidenced in osteosarcoma, for which doxorubicin...

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Bibliographic Details
Main Authors: Armstrong, J., Dass, Crispin
Format: Journal Article
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/16891