A sterol-binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing

Kes1, and other oxysterol-binding protein superfamily members, are involved in membrane and lipid trafficking through trans-Golgi network (TGN) and endosomal systems. We demonstrate that Kes1 represents a sterol-regulated antagonist of TGN/endosomal phosphatidylinositol-4-phosphate signaling. This r...

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Bibliographic Details
Main Authors: Mousley, Carl, Yuan, P., Gaur, N., Trettin, K., Nile, A., Deminoff, S., Dewar, B., Wolpert, M., MacDonald, J., Herman, P., Hinnebusch, A., Bankaitis, V.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/16747