Dynamics Analysis and Prediction of Genetic Regulation in Glycerol Metabolic Network via Structural Kinetic Modelling

Glycerol can be biologically converted to 1,3-propanediol (1,3-PD) by Klebsiella pneumoniae. In the synthesis pathway of 1,3-PD, the accumulation of an intermediary metabolite 3-hydroxypropionaldehyde (3-HPA) would cause an irreversible cessation of the dynamic system. Genetic manipulation on the ke...

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Bibliographic Details
Main Authors: Ye, J., Xu, Honglei, Huang, X., Ke, C., Feng, E.
Format: Journal Article
Published: Gordon and Breach 2015
Online Access:http://hdl.handle.net/20.500.11937/16719