DRD2/ANKK1 Taq1A (rs 1800497 C>T) genotypes are associated with susceptibility to second generation antipsychotic-induced akathisia

DRD2/ANKK1 Taq1A (rs 1800497 C>T) genotypes are associated with susceptibility to second generation antipsychotic-induced akathisia

Although the advent of atypical, second-generation antipsychotics (SGAs) has resulted in reduced likelihood of akathisia, this adverse effect remains a problem. It is known that extrapyramidal adverse effects are associated with increased drug occupancy of the dopamine 2 receptors (DRD2). The A1 all...

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Bibliographic Details
Main Authors: Lawford, B., Barnes, M., Swagell, C., Connor, J., Burton, S., Heslop, Karen, Voisey, J., Morris, C., Nyst, P., Noble, E., Young, R.
Format: Journal Article
Published: Sage Publications 2013
Subjects:
ANNK1
side effects
drug types
Akathisia
genetic association
antipsychotic drugs
dopamine 2 receptor
Online Access:http://hdl.handle.net/20.500.11937/13792

Internet

http://hdl.handle.net/20.500.11937/13792

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