The Challenge of Targeting Notch in Hematologic Malignancies

by Hernandez Tejada, Fiorela N., Galvez Silva, Jorge R., Zweidler-McKay, Patrick A.
Published 2014

The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1β and NF-κB signaling

by Trinh, Bon Q., Barengo, Nicolas, Kim, Sang Bae, Lee, Ju-Seog, Zweidler-McKay, Patrick A., Naora, Honami
Published 2015

Epigenetic Inactivation of Notch-Hes Pathway in Human B-Cell Acute Lymphoblastic Leukemia

by Kuang, Shao-Qing, Fang, Zhihong, Zweidler-McKay, Patrick A., Yang, Hui, Wei, Yue, Gonzalez-Cervantes, Emilio A., Boumber, Yanis, Garcia-Manero, Guillermo
Published 2013

Notch activation inhibits AML growth and survival: a potential therapeutic approach

by Kannan, Sankaranarayanan, Sutphin, Robert M., Hall, Mandy G., Golfman, Leonard S., Fang, Wendy, Nolo, Riitta M., Akers, Lauren J., Hammitt, Richard A., McMurray, John S., Kornblau, Steven M., Melnick, Ari M., Figueroa, Maria E., Zweidler-McKay, Patrick A.
Published 2013

Pronounced Hypoxia in Models of Murine and Human Leukemia: High Efficacy of Hypoxia-Activated Prodrug PR-104

by Benito, Juliana, Shi, Yuexi, Szymanska, Barbara, Carol, Hernan, Boehm, Ingrid, Lu, Hongbo, Konoplev, Sergej, Fang, Wendy, Zweidler-McKay, Patrick A., Campana, Dario, Borthakur, Gautam, Bueso-Ramos, Carlos, Shpall, Elizabeth, Thomas, Deborah A., Jordan, Craig T., Kantarjian, Hagop, Wilson, William R., Lock, Richard, Andreeff, Michael, Konopleva, Marina
Published 2011

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

by Benito, Juliana M., Godfrey, Laura, Kojima, Kensuke, Hogdal, Leah, Wunderlich, Mark, Geng, Huimin, Marzo, Isabel, Harutyunyan, Karine G., Golfman, Leonard, North, Phillip, Kerry, Jon, Ballabio, Erica, Chonghaile, Triona Ní, Gonzalo, Oscar, Qiu, Yihua, Jeremias, Irmela, Debose, LaKiesha, O’Brien, Eric, Ma, Helen, Zhou, Ping, Jacamo, Rodrigo, Park, Eugene, Coombes, Kevin R., Zhang, Nianxiang, Thomas, Deborah A., O’Brien, Susan, Kantarjian, Hagop M., Leverson, Joel D., Kornblau, Steven M., Andreeff, Michael, Müschen, Markus, Zweidler-McKay, Patrick A., Mulloy, James C., Letai, Anthony, Milne, Thomas A., Konopleva, Marina
Published 2015