Pharmacogenetics – Challenges and Opportunities Ahead

by Zanger, Ulrich M.
Published 2010

Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the “Missing Heritability” Problem

by Klein, Kathrin, Zanger, Ulrich M.
Published 2013

Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance

by Zanger, Ulrich M., Klein, Kathrin
Published 2013

MIRNA-DISTILLER: A Stand-Alone Application to Compile microRNA Data from Databases

by Rieger, Jessica K., Bodan, Denis A., Zanger, Ulrich M.
Published 2011

Molecular Interactions between NAFLD and Xenobiotic Metabolism

by Naik, Adviti, Belič, Aleš, Zanger, Ulrich M., Rozman, Damjana
Published 2013

Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease

by Zhang, Yijing, Klein, Kathrin, Sugathan, Aarathi, Nassery, Najlla, Dombkowski, Alan, Zanger, Ulrich M., Waxman, David J.
Published 2011

Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis

by Riedmaier, Stephan, Klein, Kathrin, Winter, Stefan, Hofmann, Ute, Schwab, Matthias, Zanger, Ulrich M.
Published 2011

Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver

by Klein, Kathrin, Winter, Stefan, Turpeinen, Miia, Schwab, Matthias, Zanger, Ulrich M.
Published 2010

LEMming: A Linear Error Model to Normalize Parallel Quantitative Real-Time PCR (qPCR) Data as an Alternative to Reference Gene Based Methods

by Feuer, Ronny, Vlaic, Sebastian, Arlt, Janine, Sawodny, Oliver, Dahmen, Uta, Zanger, Ulrich M., Thomas, Maria
Published 2015

Peroxisome proliferator-activated receptor alpha, PPARα, directly regulates transcription of cytochrome P450 CYP2C8

by Thomas, Maria, Winter, Stefan, Klumpp, Britta, Turpeinen, Miia, Klein, Kathrin, Schwab, Matthias, Zanger, Ulrich M.
Published 2015

The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes

by Thomas, Maria, Bayha, Christine, Klein, Kathrin, Müller, Simon, Weiss, Thomas S., Schwab, Matthias, Zanger, Ulrich M.
Published 2015

Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained

by Kungulovski, Goran, Nunna, Suneetha, Thomas, Maria, Zanger, Ulrich M, Reinhardt, Richard, Jeltsch, Albert
Published 2015

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

by Nies, Anne T, Niemi, Mikko, Burk, Oliver, Winter, Stefan, Zanger, Ulrich M, Stieger, Bruno, Schwab, Matthias, Schaeffeler, Elke
Published 2013

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

by Schaeffeler, Elke, Hellerbrand, Claus, Nies, Anne T, Winter, Stefan, Kruck, Stephan, Hofmann, Ute, van der Kuip, Heiko, Zanger, Ulrich M, Koepsell, Hermann, Schwab, Matthias
Published 2011

A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes

by Bucher, Joachim, Riedmaier, Stephan, Schnabel, Anke, Marcus, Katrin, Vacun, Gabriele, Weiss, Thomas S, Thasler, Wolfgang E, Nüssler, Andreas K, Zanger, Ulrich M, Reuss, Matthias
Published 2011

Coordinating Role of RXRα in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling

by Keller, Roland, Klein, Marcus, Thomas, Maria, Dräger, Andreas, Metzger, Ute, Templin, Markus F., Joos, Thomas O., Thasler, Wolfgang E., Zell, Andreas, Zanger, Ulrich M.
Published 2016

Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice

by Abshagen, Kerstin, König, Matthias, Hoppe, Andreas, Müller, Isabell, Ebert, Matthias, Weng, Honglei, Holzhütter, Herrmann-Georg, Zanger, Ulrich M., Bode, Johannes, Vollmar, Brigitte, Thomas, Maria, Dooley, Steven
Published 2015

Model-Based Characterization of Inflammatory Gene Expression Patterns of Activated Macrophages

by Rex, Julia, Albrecht, Ute, Ehlting, Christian, Thomas, Maria, Zanger, Ulrich M., Sawodny, Oliver, Häussinger, Dieter, Ederer, Michael, Feuer, Ronny, Bode, Johannes G.
Published 2016