Metabotyping of Long-Lived Mice using 1H NMR Spectroscopy

by Wijeyesekera, Anisha, Selman, Colin, Barton, Richard H., Holmes, Elaine, Nicholson, Jeremy K., Withers, Dominic J.
Published 2012

Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress

by Page, Melissa M, Sinclair, Amy, Robb, Ellen L, Stuart, Jeffrey A, Withers, Dominic J, Selman, Colin
Published 2014

Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism

by Foukas, Lazaros C, Bilanges, Benoit, Bettedi, Lucia, Pearce, Wayne, Ali, Khaled, Sancho, Sara, Withers, Dominic J, Vanhaesebroeck, Bart
Published 2013

Evidence that hematopoietic stem cell function is preserved during aging in long-lived S6K1 mutant mice

by Selman, Colin, Sinclair, Amy, Pedroni, Silvia M.A., Irvine, Elaine E., Michie, Alison M., Withers, Dominic J.
Published 2016

Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice

by Jové, Mariona, Naudí, Alba, Ramírez-Núñez, Omar, Portero-Otín, Manuel, Selman, Colin, Withers, Dominic J, Pamplona, Reinald
Published 2014

Brain Deletion of Insulin Receptor Substrate 2 Disrupts Hippocampal Synaptic Plasticity and Metaplasticity

by Costello, Derek A., Claret, Marc, Al-Qassab, Hind, Plattner, Florian, Irvine, Elaine E., Choudhury, Agharul I., Giese, K. Peter, Withers, Dominic J., Pedarzani, Paola
Published 2012

Differential Pre-mRNA Splicing Regulates Nnat Isoforms in the Hypothalamus after Gastric Bypass Surgery in Mice

by Scott, William R., Gelegen, Cigdem, Chandarana, Keval, Karra, Efthimia, Yousseif, Ahmed, Amouyal, Chloé, Choudhury, Agharul I., Andreelli, Fabrizio, Withers, Dominic J., Batterham, Rachel L.
Published 2013

PINK1 deficiency in β-cells increases basal insulin secretion and improves glucose tolerance in mice

by Deas, Emma, Piipari, Kaisa, Machhada, Asif, Li, Abi, Gutierrez-del-Arroyo, Ana, Withers, Dominic J., Wood, Nicholas W., Abramov, Andrey Y.
Published 2014

Differential Effects of Laparoscopic Sleeve Gastrectomy and Laparoscopic Gastric Bypass on Appetite, Circulating Acyl-ghrelin, Peptide YY3-36 and Active GLP-1 Levels in Non-diabeti...

by Yousseif, Ahmed, Emmanuel, Julian, Karra, Efthimia, Millet, Queensta, Elkalaawy, Mohamed, Jenkinson, Andrew D., Hashemi, Majid, Adamo, Marco, Finer, Nicholas, Fiennes, Alberic G., Withers, Dominic J., Batterham, Rachel L.
Published 2013

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice

by Killick, Richard, Scales, Georgie, Leroy, Karelle, Causevic, Mirsada, Hooper, Claudie, Irvine, Elaine E., Choudhury, Agharul I, Drinkwater, Laura, Kerr, Fiona, Al-Qassab, Hind, Stephenson, John, Yilmaz, Zehra, Giese, K. Peter, Brion, Jean-Pierre, Withers, Dominic J., Lovestone, Simon
Published 2009

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice

by Woods, Angela, Heslegrave, Amanda J., Muckett, Phillip J., Levene, Adam P., Clements, Melanie, Mobberley, Margaret, Ryder, Timothy A., Abu-Hayyeh, Shadi, Williamson, Catherine, Goldin, Robert D., Ashworth, Alan, Withers, Dominic J., Carling, David
Published 2011

Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice

by Smith, Mark A., Katsouri, Loukia, Irvine, Elaine E., Hankir, Mohammed K., Pedroni, Silvia M.A., Voshol, Peter J., Gordon, Matthew W., Choudhury, Agharul I., Woods, Angela, Vidal-Puig, Antonio, Carling, David, Withers, Dominic J.
Published 2015

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

by Yavari, Arash, Stocker, Claire J., Ghaffari, Sahar, Wargent, Edward T., Steeples, Violetta, Czibik, Gabor, Pinter, Katalin, Bellahcene, Mohamed, Woods, Angela, Martínez de Morentin, Pablo B., Cansell, Céline, Lam, Brian Y.H., Chuster, André, Petkevicius, Kasparas, Nguyen-Tu, Marie-Sophie, Martinez-Sanchez, Aida, Pullen, Timothy J., Oliver, Peter L., Stockenhuber, Alexander, Nguyen, Chinh, Lazdam, Merzaka, O’Dowd, Jacqueline F., Harikumar, Parvathy, Tóth, Mónika, Beall, Craig, Kyriakou, Theodosios, Parnis, Julia, Sarma, Dhruv, Katritsis, George, Wortmann, Diana D.J., Harper, Andrew R., Brown, Laurence A., Willows, Robin, Gandra, Silvia, Poncio, Victor, de Oliveira Figueiredo, Márcio J., Qi, Nathan R., Peirson, Stuart N., McCrimmon, Rory J., Gereben, Balázs, Tretter, László, Fekete, Csaba, Redwood, Charles, Yeo, Giles S.H., Heisler, Lora K., Rutter, Guy A., Smith, Mark A., Withers, Dominic J., Carling, David, Sternick, Eduardo B., Arch, Jonathan R.S., Cawthorne, Michael A., Watkins, Hugh, Ashrafian, Houman
Published 2016