National Differences in Requirements for Ethical and Competent Authority Approval for a Multinational Vaccine Trial under the EU Directive 2001/20/EC

by van Doorn, Eva, Hak, Eelko, Wilffert, Bob
Published 2015

From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics

by Wilffert, Bob, Swen, Jesse, Mulder, Hans, Touw, Daan, Maitland-Van der Zee, Anke-Hilse, Deneer, Vera
Published 2010

A Model Based Cost-Effectiveness Analysis of Routine Genotyping for CYP2D6 among Older, Depressed Inpatients Starting Nortriptyline Pharmacotherapy

by Berm, Elizabeth J. J., Gout-Zwart, Judith J., Luttjeboer, Jos, Wilffert, Bob, Postma, Maarten J.
Published 2016

The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors—Is Pharmacogenetics the Key?

by Daud, Aizati N. A., Bergman, Jorieke E. H., Kerstjens-Frederikse, Wilhelmina S., Groen, Henk, Wilffert, Bob
Published 2016

Economic Evaluations of Pharmacogenetic and Pharmacogenomic Screening Tests: A Systematic Review. Second Update of the Literature

by Berm, Elizabeth J. J., de Looff, Margot, Wilffert, Bob, Boersma, Cornelis, Annemans, Lieven, Vegter, Stefan, van Boven, Job F. M., Postma, Maarten J.
Published 2016

Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication

by Vehof, Jelle, Risselada, Arne J., Al Hadithy, Asmar F. Y., Burger, Huibert, Snieder, Harold, Wilffert, Bob, Arends, Johan, Wunderink, Lex, Knegtering, Henrikus, Wiersma, Durk, Cohen, Dan, Mulder, Hans, Bruggeman, Richard
Published 2011

P-Glycoprotein-Mediated Drug Interactions in Pregnancy and Changes in the Risk of Congenital Anomalies: A Case-Reference Study

by Daud, Aizati N. A., Bergman, Jorieke E. H., Bakker, Marian K., Wang, Hao, Kerstjens-Frederikse, Wilhelmina S., de Walle, Hermien E. K., Groen, Henk, Bos, Jens H. J., Hak, Eelko, Wilffert, Bob
Published 2015

Effects and cost-effectiveness of pharmacogenetic screening for CYP2D6 among older adults starting therapy with nortriptyline or venlafaxine: study protocol for a pragmatic randomi...

by Berm, Elizabeth JJ, Hak, Eelko, Postma, Maarten, Boshuisen, Marjolein, Breuning, Laura, Brouwers, Jacobus RBJ, Dhondt, Ton, Jansen, Paul AF, Kok, Rob M, Maring, Jan G, van Marum, Rob, Mulder, Hans, Voshaar, Richard C Oude, Risselada, Arne J, Venema, Harry, Vleugel, Liesbeth, Wilffert, Bob
Published 2015

Likelihood of mechanistic roles for dopaminergic, serotonergic and glutamatergic receptors in tardive dyskinesia: A comparison of genetic variants in two independent patient popula...

by Ivanova, Svetlana A, Loonen, Anton JM, Bakker, P Roberto, Freidin, Maxim B, ter Woerds, Nienke J, Al Hadithy, Asmar FY, Semke, Arkadiy V, Fedorenko, Olga Yu, Brouwers, Jacobus RBJ, Bokhan, Nikolay A, van Os, Jim, van Harten, Peter N, Wilffert, Bob
Published 2016