Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancy

by Wang, Qinhao, Ru, Yi, Zhong, Daixing, Zhang, Jing, Yao, Libo, Li, Xia
Published 2014

The chimeric ubiquitin ligase SH2-U-box inhibits the growth of imatinib-sensitive and resistant CML by targeting the native and T315I-mutant BCR-ABL

by Ru, Yi, Wang, Qinhao, Liu, Xiping, Zhang, Mei, Zhong, Daixing, Ye, Mingxiang, Li, Yuanchun, Han, Hua, Yao, Libo, Li, Xia
Published 2016

Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma

by Li, Xia, Liu, Yuexin, Granberg, Kirsi J., Wang, Qinhao, Moore, Lynette M., Ji, Ping, Gumin, Joy, Sulman, Erik P., Calin, George A., Haapasalo, Hannu, Nykter, Matti, Shmulevich, Ilya, Fuller, Gregory N., Lang, Frederick F., Zhang, Wei
Published 2014