Plasma & subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis

by Abdul Aziz, Mohd. Hafiz, Udy, Andrew A., Wallis, Steven C., Roberts, Michael S., Lipman, Jeffrey, Roberts, Jason A.
Published 2014

Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

by Shekar, Kiran, Roberts, Jason A., Barnett, Adrian G., Diab, Sara, Wallis, Steven C., Fung, Yoke L., Fraser, John F.
Published 2015

Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomized controlled trial of continuous infusion versus intermittent b...

by Jamal, Janattul-Ain, Mat Nor, Mohd Basri, Mohamad Nor, Fariz Safhan, Udy, Andrew A, Wallis, Steven C, Lipman, Jeffrey, Roberts, Jason A.
Published 2015

The BLISS study: Beta-Lactam infusion in severe sepsis-randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sep...

by Abdul Aziz, Mohd. Hafiz, Sulaiman, Helmi, Mat Nor, Mohd. Basri, Rai, Vineya, Wong, K., Hasan , Mohd Shahnaz, Wallis, Steven C, Lipman, Jeffrey, Staatz, Christine E., Roberts, Jason A.
Published 2015

Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controlled trial of continuous infusion versus intermitten...

by Jamal, Janattul-Ain, Roberts, Darren M., Udy, Andrew A, Mat Nor, Mohd Basri, Mohamad Nor, Fariz Safhan, Wallis, Steven C, Lipman, Jeffrey, Roberts, Jason A.
Published 2015

Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit

by Abdul Aziz, Mohd. Hafiz, Abd. Rahman, Nurul Azrin, Mat Nor, Mohd Basri, Sulaiman, Helmi, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A., Staatz, Christine E.
Published 2016

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill pa...

by Roberts, Jason A, De Waele, Jan J, Dimopoulos, George, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C, Lipman, Jeffrey
Published 2012

Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended...

by Carlier, Mieke, Carrette, Sofie, Roberts, Jason A, Stove, Veronique, Verstraete, Alain, Hoste, Eric, Depuydt, Pieter, Decruyenaere, Johan, Lipman, Jeffrey, Wallis, Steven C, De Waele, Jan J
Published 2013

Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: results from an ex vivo study

by Shekar, Kiran, Roberts, Jason A, Mcdonald, Charles I, Ghassabian, Sussan, Anstey, Chris, Wallis, Steven C, Mullany, Daniel V, Fung, Yoke L, Fraser, John F
Published 2015

Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?

by Udy, Andrew A, Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C, Patel, Kashyap, Kirkpatrick, Carl MJ, Kruger, Peter S, Paterson, David L, Roberts, Michael S, Roberts, Jason A
Published 2015

Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

by Udy, Andrew A, Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C, Roberts, Jason A, Lipman, Jeffrey
Published 2014

The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study

by Shekar, Kiran, Fraser, John F, Taccone, Fabio Silvio, Welch, Susan, Wallis, Steven C, Mullany, Daniel V, Lipman, Jeffrey, Roberts, Jason A
Published 2014

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observat...

by Abdul Aziz, Mohd. Hafiz, Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel M., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A.
Published 2015

Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critic...

by Abdul Aziz, Mohd. Hafiz, Sulaiman, Helmi, Mat Nor, Mohd Basri, Rai, Vineya, Wong, K., Hasan, Mohd Shahnaz, Abd. Rahman, Nurul Azrin, Jamal, Janattul-Ain, Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E., Roberts, Jason A.
Published 2016

Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation

by Sinnah, Fabrice, Shekar, Kiran, Abdul Aziz, Mohd. Hafiz, Buscher, Hergen, Diab, Sara, Fisquet, Stephanie, Fung, Yoke, McDonald, Charles, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan, Xie, Jiao, Fraser, John, Roberts, Jason A.
Published 2017

The DALI study: defining antibiotic levels in intensive care unit patients: prolonged infusion of beta-lactam antibiotics in critically ill patients

by Abdul Aziz, Mohd. Hafiz, Roberts, Jason A., Akova, Murat, Basetti, Matteo, De Waele, Jan, Dimopoulos, George, Kaukonen, Maija, Koulenti, Despoina, Martin, Claude, Montravers, Paul, Rello, Jordi, Rhodes, Alan, Starr, Therese, Wallis, Steven C., Lipman, Jeffrey
Published 2013

Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation

by Shekar, Kiran, Roberts, Jason A, Mcdonald, Charles I, Fisquet, Stephanie, Barnett, Adrian G, Mullany, Daniel V, Ghassabian, Sussan, Wallis, Steven C, Fung, Yoke L, Smith, Maree T, Fraser, John F
Published 2012

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study

by Blot, Stijn, Koulenti, Despoina, Akova, Murat, Bassetti, Matteo, De Waele, Jan J, Dimopoulos, George, Kaukonen, Kirsi-Maija, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C, Lipman, Jeffrey, Roberts, Jason A
Published 2014

SaMpling Antibiotics in Renal Replacement Therapy (SMARRT): an observational pharmacokinetic study in critically ill patients

by Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese, Lipman, Jeffrey
Published 2016

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Inte...

by Sinnollareddy, Mahipal G, Roberts, Jason A, Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C, Dimopoulos, George
Published 2015