A Broad Overview and Review of CRISPR-Cas Technology and Stem Cells

by Waddington, Simon N., Privolizzi, Riccardo, Karda, Rajvinder, O’Neill, Helen C.
Published 2016

Specific inhibition of c-Jun N-terminal kinase delays preterm labour and reduces mortality

by Pirianov, Grisha, MacIntyre, David A, Lee, Yun, Waddington, Simon N, Terzidou, Vasso, Mehmet, Huseyin, Bennett, Phillip R
Published 2015

Perinatal Gene Transfer to the Liver

by McKay, Tristan R, Rahim, Ahad A, Buckley, Suzanne M.K, Ward, Natalie J, Chan, Jerry K.Y, Howe, Steven J, Waddington, Simon N
Published 2011

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

by Osellame, Laura D., Rahim, Ahad A., Hargreaves, Iain P., Gegg, Matthew E., Richard-Londt, Angela, Brandner, Sebastian, Waddington, Simon N., Schapira, Anthony H.V., Duchen, Michael R.
Published 2013

Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics

by Migale, Roberta, MacIntyre, David A., Cacciatore, Stefano, Lee, Yun S., Hagberg, Henrik, Herbert, Bronwen R., Johnson, Mark R., Peebles, Donald, Waddington, Simon N., Bennett, Phillip R.
Published 2016

Regionally-Specified Second Trimester Fetal Neural Stem Cells Reveals Differential Neurogenic Programming

by Fan, Yiping, Marcy, Guillaume, Lee, Eddy S. M., Rozen, Steve, Mattar, Citra N. Z., Waddington, Simon N., Goh, Eyleen L. K., Choolani, Mahesh, Chan, Jerry K. Y.
Published 2014

Evidence for Contribution of CD4+CD25+ Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery

by Nivsarkar, Megha S., Buckley, Suzanne M. K., Parker, Alan L., Perocheau, Dany, McKay, Tristan R., Rahim, Ahad A., Howe, Steven J., Waddington, Simon N.
Published 2015

Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates

by Mattar, Citra N., Wong, Andrew M. S., Hoefer, Klemens, Alonso-Ferrero, Maria E., Buckley, Suzanne M. K., Howe, Steven J., Cooper, Jonathan D., Waddington, Simon N., Chan, Jerry K. Y., Rahim, Ahad A.
Published 2015

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming

by Hawkins, Kate E., Joy, Shona, Delhove, Juliette M.K.M., Kotiadis, Vassilios N., Fernandez, Emilio, Fitzpatrick, Lorna M., Whiteford, James R., King, Peter J., Bolanos, Juan P., Duchen, Michael R., Waddington, Simon N., McKay, Tristan R.
Published 2016

Perinatal systemic gene delivery using adeno-associated viral vectors

by Karda, Rajvinder, Buckley, Suzanne M. K., Mattar, Citra N., Ng, Joanne, Massaro, Giulia, Hughes, Michael P., Kurian, Manju A., Baruteau, Julien, Gissen, Paul, Chan, Jerry K. Y., Bacchelli, Chiara, Waddington, Simon N., Rahim, Ahad A.
Published 2014

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage

by Binny, Christopher, McIntosh, Jenny, Della Peruta, Marco, Kymalainen, Hanna, Tuddenham, Edward G. D., Buckley, Suzanne M. K., Waddington, Simon N., McVey, John H., Spence, Yunyu, Morton, Christopher L., Thrasher, Adrian J., Gray, John T., Castellino, Francis J., Tarantal, Alice F., Davidoff, Andrew M., Nathwani, Amit C.
Published 2012

The CD46 and Jagged1 interaction is critical for human T helper 1 immunity

by Le Friec, Gaëlle, Sheppard, Devon, Whiteman, Pat, Karsten, Christian M., Shamoun, Salley Al-Tilib, Laing, Adam, Bugeon, Laurence, Dallman, Margaret J., Melchionna, Teresa, Chillakuri, Chandramouli, Smith, Richard A., Drouet, Christian, Couzi, Lionel, Fremeaux-Bacchi, Veronique, Köhl, Jörg, Waddington, Simon N., McDonnell, James M., Baker, Alastair, Handford, Penny A., Lea, Susan M., Kemper, Claudia
Published 2012

In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters

by Buckley, Suzanne M. K., Delhove, Juliette M. K. M., Perocheau, Dany P., Karda, Rajvinder, Rahim, Ahad A., Howe, Steven J., Ward, Natalie J., Birrell, Mark A., Belvisi, Maria G., Arbuthnot, Patrick, Johnson, Mark R., Waddington, Simon N., McKay, Tristan R.
Published 2015

Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis

by Banushi, Blerida, Forneris, Federico, Straatman-Iwanowska, Anna, Strange, Adam, Lyne, Anne-Marie, Rogerson, Clare, Burden, Jemima J., Heywood, Wendy E., Hanley, Joanna, Doykov, Ivan, Straatman, Kornelis R., Smith, Holly, Bem, Danai, Kriston-Vizi, Janos, Ariceta, Gema, Risteli, Maija, Wang, Chunguang, Ardill, Rosalyn E., Zaniew, Marcin, Latka-Grot, Julita, Waddington, Simon N., Howe, S. J., Ferraro, Francesco, Gjinovci, Asllan, Lawrence, Scott, Marsh, Mark, Girolami, Mark, Bozec, Laurent, Mills, Kevin, Gissen, Paul
Published 2016