Hypoxia reduces CD138 expression and induces an immature and stem cell-like transcriptional program in myeloma cells

by KAWANO, YAWARA, KIKUKAWA, YOSHITAKA, FUJIWARA, SHIHO, WADA, NAOKO, OKUNO, YUTAKA, MITSUYA, HIROAKI, HATA, HIROYUKI
Published 2013

Lactate, a putative survival factor for myeloma cells, is incorporated by myeloma cells through monocarboxylate transporters 1

by Fujiwara, Shiho, Wada, Naoko, Kawano, Yawara, Okuno, Yutaka, Kikukawa, Yoshitaka, Endo, Shinya, Nishimura, Nao, Ueno, Nina, Mitsuya, Hiroaki, Hata, Hiroyuki
Published 2015

Multiple myeloma cells expressing low levels of CD138 have an immature phenotype and reduced sensitivity to lenalidomide

by KAWANO, YAWARA, FUJIWARA, SHIHO, WADA, NAOKO, IZAKI, MIKIKO, YUKI, HIROMICHI, OKUNO, YUTAKA, IYAMA, KENICHI, YAMASAKI, HIROSHI, SAKAI, AKIRA, MITSUYA, HIROAKI, HATA, HIROYUKI
Published 2012

SGLT5 Reabsorbs Fructose in the Kidney but Its Deficiency Paradoxically Exacerbates Hepatic Steatosis Induced by Fructose

by Fukuzawa, Taku, Fukazawa, Masanori, Ueda, Otoya, Shimada, Hideaki, Kito, Aki, Kakefuda, Mami, Kawase, Yosuke, Wada, Naoko A., Goto, Chisato, Fukushima, Naoshi, Jishage, Kou-ichi, Honda, Kiyofumi, King, George L., Kawabe, Yoshiki
Published 2013

Novel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor

by Ueda, Otoya, Tateishi, Hiromi, Higuchi, Yoshinobu, Fujii, Etsuko, Kato, Atsuhiko, Kawase, Yosuke, Wada, Naoko A., Tachibe, Takanori, Kakefuda, Mami, Goto, Chisato, Kawaharada, Makoto, Shimaoka, Shin, Hattori, Kunihiro, Jishage, Kou-ichi
Published 2013

Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice

by Tateno, Chise, Kawase, Yosuke, Tobita, Yoshimi, Hamamura, Satoko, Ohshita, Hiroki, Yokomichi, Hiroshi, Sanada, Harumi, Kakuni, Masakazu, Shiota, Akira, Kojima, Yuha, Ishida, Yuji, Shitara, Hiroshi, Wada, Naoko A., Tateishi, Hiromi, Sudoh, Masayuki, Nagatsuka, Shin-ichiro, Jishage, Kou-ichi, Kohara, Michinori
Published 2015

Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells

by WADA, NAOKO, KAWANO, YAWARA, FUJIWARA, SHIHO, KIKUKAWA, YOSHITAKA, OKUNO, YUTAKA, TASAKI, MASAYOSHI, UEDA, MITSUHARU, ANDO, YUKIO, YOSHINAGA, KAZUYA, RI, MASAKI, IIDA, SHINSUKE, NAKASHIMA, TAKAYUKI, SHIOTSU, YUKIMASA, MITSUYA, HIROAKI, HATA, HIROYUKI
Published 2014