GSK3 and Alzheimer’s Disease: Facts and Fiction…

by Kremer, Anna, Louis, Justin V., Jaworski, Tomasz, Van Leuven, Fred
Published 2011

Protein Tau: Prime Cause of Synaptic and Neuronal Degeneration in Alzheimer's Disease

by Crespo-Biel, Natalia, Theunis, Clara, Van Leuven, Fred
Published 2012

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease

by Van der Auwera, Ingrid, Wera, Stefaan, Van Leuven, Fred, Henderson, Samuel T
Published 2005

Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice

by Heneka, Michael T, Sastre, Magdalena, Dumitrescu-Ozimek, Lucia, Dewachter, Ilse, Walter, Jochen, Klockgether, Thomas, Van Leuven, Fred
Published 2005

Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer’s disease

by Kukreja, Lokesh, Kujoth, Gregory C, Prolla, Tomas A, Van Leuven, Fred, Vassar, Robert
Published 2014

Age-Related Impairment of Ultrasonic Vocalization in Tau.P301L Mice: Possible Implication for Progressive Language Disorders

by Menuet, Clément, Cazals, Yves, Gestreau, Christian, Borghgraef, Peter, Gielis, Lies, Dutschmann, Mathias, Van Leuven, Fred, Hilaire, Gérard
Published 2011

Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase

by Maurin, Hervé, Lechat, Benoit, Dewachter, Ilse, Ris, Laurence, Louis, Justin V, Borghgraef, Peter, Devijver, Herman, Jaworski, Tomasz, Van Leuven, Fred
Published 2013

Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice

by Rat, Dorothea, Schmitt, Ulrich, Tippmann, Frank, Dewachter, Ilse, Theunis, Clara, Wieczerzak, Ewa, Postina, Rolf, van Leuven, Fred, Fahrenholz, Falk, Kojro, Elzbieta
Published 2011

Increasing Brain Protein O-GlcNAc-ylation Mitigates Breathing Defects and Mortality of Tau.P301L Mice

by Borghgraef, Peter, Menuet, Clément, Theunis, Clara, Louis, Justin V., Devijver, Herman, Maurin, Hervé, Smet-Nocca, Caroline, Lippens, Guy, Hilaire, Gerard, Gijsen, Harrie, Moechars, Dieder, Van Leuven, Fred
Published 2013

Tauopathy Differentially Affects Cell Adhesion Molecules in Mouse Brain: Early Down-Regulation of Nectin-3 in Stratum Lacunosum Moleculare

by Maurin, Hervé, Seymour, Claire Marie, Lechat, Benoit, Borghgraef, Peter, Devijver, Herman, Jaworski, Tomasz, Schmidt, Mathias V., Kuegler, Sebastian, Van Leuven, Fred
Published 2013

Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes

by Pajares, Marta, Jiménez-Moreno, Natalia, García-Yagüe, Ángel J., Escoll, Maribel, de Ceballos, María L., Van Leuven, Fred, Rábano, Alberto, Yamamoto, Masayuki, Rojo, Ana I., Cuadrado, Antonio
Published 2016

Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β′-site increases Aβ generation†

by Zhou, Lujia, Brouwers, Nathalie, Benilova, Iryna, Vandersteen, Annelies, Mercken, Marc, Van Laere, Koen, Van Damme, Philip, Demedts, David, Van Leuven, Fred, Sleegers, Kristel, Broersen, Kerensa, Van Broeckhoven, Christine, Vandenberghe, Rik, De Strooper, Bart
Published 2011

Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy

by Theunis, Clara, Crespo-Biel, Natalia, Gafner, Valérie, Pihlgren, Maria, López-Deber, María Pilar, Reis, Pedro, Hickman, David T., Adolfsson, Oskar, Chuard, Nathalie, Ndao, Dorin Mlaki, Borghgraef, Peter, Devijver, Herman, Van Leuven, Fred, Pfeifer, Andrea, Muhs, Andreas
Published 2013

Early Structural and Functional Defects in Synapses and Myelinated Axons in Stratum Lacunosum Moleculare in Two Preclinical Models for Tauopathy

by Maurin, Hervé, Chong, Seon-Ah, Kraev, Igor, Davies, Heather, Kremer, Anna, Seymour, Claire Marie, Lechat, Benoit, Jaworski, Tomasz, Borghgraef, Peter, Devijver, Herman, Callewaert, Geert, Stewart, Michael G., Van Leuven, Fred
Published 2014