A New Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8 Bound to DNA Gyrase Gives Fresh Insight into the Mechanism of Inhibition

by Hearnshaw, Stephen J., Edwards, Marcus J., Stevenson, Clare E., Lawson, David M., Maxwell, Anthony
Published 2014

Substrate-Assisted Catalysis in Polyketide Reduction Proceeds via a Phenolate Intermediate

by Schäfer, Martin, Stevenson, Clare E.M., Wilkinson, Barrie, Lawson, David M., Buttner, Mark J.
Published 2016

Bacterial Rotary Export ATPases Are Allosterically Regulated by the Nucleotide Second Messenger Cyclic-di-GMP*

by Trampari, Eleftheria, Stevenson, Clare E. M., Little, Richard H., Wilhelm, Thomas, Lawson, David M., Malone, Jacob G.
Published 2015

Investigation of DNA sequence recognition by a streptomycete MarR family transcriptional regulator through surface plasmon resonance and X-ray crystallography

by Stevenson, Clare E. M., Assaad, Aoun, Chandra, Govind, Le, Tung B. K., Greive, Sandra J., Bibb, Mervyn J., Lawson, David M.
Published 2013

Structural Insight into How Streptomyces coelicolor Maltosyl Transferase GlgE Binds α-Maltose 1-Phosphate and Forms a Maltosyl-enzyme Intermediate

by Syson, Karl, Stevenson, Clare E. M., Rashid, Abdul M., Saalbach, Gerhard, Tang, Minhong, Tuukkanen, Anne, Svergun, Dmitri I., Withers, Stephen G., Lawson, David M., Bornemann, Stephen
Published 2014

Mitoxantrone and Analogues Bind and Stabilize i-Motif Forming DNA Sequences

by Wright, Elisé P., Day, Henry A., Ibrahim, Ali M., Kumar, Jeethendra, Boswell, Leo J. E., Huguin, Camille, Stevenson, Clare E. M., Pors, Klaus, Waller, Zoë A. E.
Published 2016

Ligand-bound Structures and Site-directed Mutagenesis Identify the Acceptor and Secondary Binding Sites of Streptomyces coelicolor Maltosyltransferase GlgE*

by Syson, Karl, Stevenson, Clare E. M., Miah, Farzana, Barclay, J. Elaine, Tang, Minhong, Gorelik, Andrii, Rashid, Abdul M., Lawson, David M., Bornemann, Stephen
Published 2016

Structural determinants of reductive terpene cyclization in iridoid biosynthesis

by Kries, Hajo, Caputi, Lorenzo, Stevenson, Clare E. M., Kamileen, Mohammed O., Sherden, Nathaniel H., Geu-Flores, Fernando, Lawson, David M., O’Connor, Sarah E.
Published 2015

Crystal structure of a novel two domain GH78 family α-rhamnosidase from Klebsiella oxytoca with rhamnose bound

by O’Neill, Ellis C, Stevenson, Clare E M, Paterson, Michael J, Rejzek, Martin, Chauvin, Anne-Laure, Lawson, David M, Field, Robert A
Published 2015

Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1)*

by O'Neill, Ellis C., Stevenson, Clare E. M., Tantanarat, Krit, Latousakis, Dimitrios, Donaldson, Matthew I., Rejzek, Martin, Nepogodiev, Sergey A., Limpaseni, Tipaporn, Field, Robert A., Lawson, David M.
Published 2015

Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity

by Stavrinides, Anna, Tatsis, Evangelos C., Caputi, Lorenzo, Foureau, Emilien, Stevenson, Clare E. M., Lawson, David M., Courdavault, Vincent, O'Connor, Sarah E.
Published 2016