‘Next-generation’ genome wide association studies

by Hopper, J, Makalic, E, Schmidt, D, Bui, M, Stone, J, Kapuscinski, M, Park, D, Jenkins, M, Southey, M
Published 2012

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

by Osborne, N., Gurrin, N., Allen, K., Constantine, C., Delatycki, M., McLaren, C., Gertig, D., Anderson, G., Southey, M., Olynyk, John, Powell, L., Hopper, J., Giles, G., English, D.
Published 2010

The Natural History of Serum Iron Indices for HFE C282Y Homozygosity Associated With Hereditary Hemochromatosis

by Gurrin, L., Osborne, N., Constantine, C., McLaren, C., English, D., Gertig, D., Delatycki, M., Southey, M., Hopper, J., Giles, G., Anderson, G., Olynyk, John, Powell, L., Allen, K.
Published 2008

Iron-overload-related disease in HFE hereditary hemochromatosis

by Allen, K., Gurrin, L., Constantine, C., Osborne, N., Delatycki, M., Nicoll, A., McLaren, C., Bahlo, M., Nisselle, A., Vulpe, C., Anderson, G., Southey, M., Giles, G., English, D., Hopper, J., Olynyk, John, Powell, L., Gertig, D.
Published 2008

Morphological predictors of BRCA1 germline mutations in young women with breast cancer

by Southey, M C, Ramus, S J, Dowty, J G, Smith, L D, Tesoriero, A A, Wong, E E M, Dite, G S, Jenkins, M A, Byrnes, G B, Winship, I, Phillips, K-A, Giles, G G, Hopper, J L
Published 2011

Prospective validation of the breast cancer risk prediction model BOADICEA and a batch-mode version BOADICEACentre

by MacInnis, R J, Bickerstaffe, A, Apicella, C, Dite, G S, Dowty, J G, Aujard, K, Phillips, K-A, Weideman, P, Lee, A, Terry, M B, Giles, G G, Southey, M C, Antoniou, A C, Hopper, J L
Published 2013

Reproductive risk factors and oestrogen/progesterone receptor-negative breast cancer in the Breast Cancer Family Registry

by Work, M E, John, E M, Andrulis, I L, Knight, J A, Liao, Y, Mulligan, A M, Southey, M C, Giles, G G, Dite, G S, Apicella, C, Hibshoosh, H, Hopper, J L, Terry, M B
Published 2014

HFE C282Y/H63D Compound Heterozygotes Are at Low Risk of Hemochromatosis-Related Morbidity

by Gurrin, L., Bertalli, N., Dalton, G., Osborne, N., Constantine, C., McLaren, C., English, D., Gertig, D., Delatycki, M., Nicoll, A., Southey, M., Hopper, J., Giles, G., Anderson, G., Olynyk, John, Powell, L., Allen, K., Bahlo, M., Vulpe, C., Forrest, S., Fletcher, A.
Published 2009

A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis

by Constantine, C., Anderson, G., Vulpe, C., McLaren, C., Bahlo, M., Yeap, H., Gertig, D., Osborne, N., Bertalli, N., Beckman, K., Chen, V., Matak, P., McKie, A., Delatycki, M., Olynyk, John, English, D., Southey, M., Giles, G., Hopper, J., Allen, K., Gurrin, L.
Published 2009

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

by Kote-Jarai, Z., Amin Al Olama, A., Leongamornlert, D., Tymrakiewicz, M., Saunders, E., Guy, M., Giles, G. G., Severi, G., Southey, M., Hopper, J. L., Sit, K. C., Harris, J. M., Batra, J., Spurdle, A. B., Clements, J. A., Hamdy, F., Neal, D., Donovan, J., Muir, K., Pharoah, P. D. P., Chanock, S. J., Brown, N., Benlloch, S., Castro, E., Mahmud, N., O’Brien, L., Hall, A., Sawyer, E., Wilkinson, R., Easton, D. F., Eeles, R. A.
Published 2011

A multi-centre international quality control study comparing mRNA splicing assay protocols and reporting practices from the ENIGMA consortium

by Whiley, P, Walker, LC, De LA Hoya, M, Wappenschmidt, B, Becker, A, Blanco, A, Blok, MJ, Caligo, MA, Chatfield, C, Couch, F, Diez, O, Fachal, L, Guidugli, L, Enríquez, S Gutiérrez, Hansen, T, Houdayer, C, Imrie, S, Lafferty, A, Lázaro, C, Menéndez, M, Montagna, M, Montalbán, G, Santamariña, M, Pederson, I Sokilde, Southey, M, Tancredi, M, Tenès, A, Thomassen, M, Van Overeem Vega, A, Spurdle, AB, Brown, MA
Published 2012

Tumour morphology predicts PALB2 germline mutation status

by Teo, Z L, Provenzano, E, Dite, G S, Park, D J, Apicella, C, Sawyer, S D, James, P A, Mitchell, G, Trainer, A H, Lindeman, G J, Shackleton, K, Cicciarelli, L, Buys, S S, Andrulis, I L, Mulligan, A M, Glendon, G, John, E M, Terry, M B, Daly, M, Odefrey, F A, Nguyen-Dumont, T, Giles, G G, Dowty, J G, Winship, I, Goldgar, D E, Hopper, J L, Southey, M C
Published 2013

Multigene testing of moderate-risk genes: be mindful of the missense

by Young, E L, Feng, B J, Stark, A W, Damiola, F, Durand, G, Forey, N, Francy, T C, Gammon, A, Kohlmann, W K, Kaphingst, K A, McKay-Chopin, S, Nguyen-Dumont, T, Oliver, J, Paquette, A M, Pertesi, M, Robinot, N, Rosenthal, J S, Vallee, M, Voegele, C, Hopper, J L, Southey, M C, Andrulis, I L, John, E M, Hashibe, M, Gertz, J, Le Calvez-Kelm, F, Lesueur, F, Goldgar, D E, Tavtigian, S V
Published 2016

PREDICT Plus: development and validation of a prognostic model for early breast cancer that includes HER2

by Wishart, G C, Bajdik, C D, Dicks, E, Provenzano, E, Schmidt, M K, Sherman, M, Greenberg, D C, Green, A R, Gelmon, K A, Kosma, V-M, Olson, J E, Beckmann, M W, Winqvist, R, Cross, S S, Severi, G, Huntsman, D, Pylkäs, K, Ellis, I, Nielsen, T O, Giles, G, Blomqvist, C, Fasching, P A, Couch, F J, Rakha, E, Foulkes, W D, Blows, F M, Bégin, L R, van't Veer, L J, Southey, M, Nevanlinna, H, Mannermaa, A, Cox, A, Cheang, M, Baglietto, L, Caldas, C, Garcia-Closas, M, Pharoah, P D P
Published 2012

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk

by Stevens, K N, Garcia-Closas, M, Fredericksen, Z, Kosel, M, Pankratz, V S, Hopper, J L, Dite, G S, Apicella, C, Southey, M C, Schmidt, M K, Broeks, A, Van ‘t Veer, L J, Tollenaar, R A E M, Fasching, P A, Beckmann, M W, Hein, A, Ekici, A B, Johnson, N, Peto, J, dos Santos Silva, I, Gibson, L, Sawyer, E, Tomlinson, I, Kerin, M J, Chanock, S, Lissowska, J, Hunter, D J, Hoover, R N, Thomas, G D, Milne, R L, Pérez, JI Arias, González-Neira, A, Benítez, J, Burwinkel, B, Meindl, A, Schmutzler, R K, Bartrar, C R, Hamann, U, Ko, Y D, Brüning, T, Chang-Claude, J, Hein, R, Wang-Gohrke, S, Dörk, T, Schürmann, P, Bremer, M, Hillemanns, P, Bogdanova, N, Zalutsky, J V, Rogov, Y I, Antonenkova, N, Lindblom, A, Margolin, S, Mannermaa, A, Kataja, V, Kosma, V-M, Hartikainen, J, Chenevix-Trench, G, Chen, X, Peterlongo, P, Bonanni, B, Bernard, L, Manoukian, S, Wang, X, Cerhan, J, Vachon, C M, Olson, J, Giles, G G, Baglietto, L, McLean, C A, Severi, G, John, E M, Miron, A, Winqvist, R, Pylkäs, K, Jukkola-Vuorinen, A, Grip, M, Andrulis, I, Knight, J A, Glendon, G, Mulligan, A M, Cox, A, Brock, I W, Elliott, G, Cross, S S, Pharoah, P P, Dunning, A M, Pooley, K A, Humphreys, M K, Wang, J, Kang, D, Yoo, K-Y, Noh, D-Y, Sangrajrang, S, Gabrieau, V, Brennan, P, McKay, J, Anton-Culver, H, Ziogas, A, Couch, F J, Easton, D F
Published 2011

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

by Shen, H., Fridley, B.L., Song, H.L., Lawrenson, K., Cunningham, J.M., Ramus, S.J., Cicek, M.S., Tyrer, J., Stram, D., Larson, M.C., Kobel, M., Ziogas, A., Zheng, W., Yang, H.P., Wu, A.H., Wozniak, E.L., Woo, Y.L., Winterhoff, B., Wik, E., Whittemore, A.S., Wentzensen, N., Weber, R.P., Vitonis, A.F., Vincent, D., Vierkant, R.A., Vergote, I., Van Den Berg, D., Van Altena, A.M., Tworoger, S.S., Thompson, P.J., Tessier, D.C., Terry, K.L., Teo, S.H., Templeman, C., Stram, D.O., Southey, M.C., Sieh, W., Siddiqui, N., Shvetsov, Y.B., Shu, X.O., Shridhar, V., Wang-Gohrke, S., Severi, G., Schwaab, I., Salvesen, H.B., Rzepecka, I.K., Runnebaum, I.B., Rossing, M.A., Rodriguez-Rodriguez, L., Risch, H.A., Renner, S.P., Poole, E.M., Pike, M.C., Phelan, C.M., Pelttari, L.M., Pejovic, T., Paul, J., Orlow, I., Omar, S.Z., Olson, S.H., Odunsi, K., Nickels, S., Nevanlinna, H., Ness, R.B., Narod, S.A., Nakanishi, T., Moysich, K.B., Monteiro, A.N.A., Moes-Sosnowska, J., Modugno, F., Menon, U., McLaughlin, J.R., McGuire, V., Matsuo, K., Adenan, N.A.M., Massuger, L.F.A.G., Lurie, G., Lundvall, L., Lubinski, J., Lissowska, J., Levine, D.A., Leminen, A., Lee, A.W., Le, N.D., Lambrechts, S., Lambrechts, D., Kupryjanczyk, J., Krakstad, C., Konecny, G.E., Kjaer, S.K., Kiemeney, L.A., Kelemen, L.E., Keeney, G.L., Karlan, B.Y., Karevan, R., Kalli, K.R., Kajiyama, H., Ji, B.T., Jensen, A., Jakubowska, A.
Published 2013

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

by Agarwal, D, Pineda, S, Michailidou, K, Herranz, J, Pita, G, Moreno, L T, Alonso, M R, Dennis, J, Wang, Q, Bolla, M K, Meyer, K B, Menéndez-Rodríguez, P, Hardisson, D, Mendiola, M, González-Neira, A, Lindblom, A, Margolin, S, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, Matsuo, K, Ito, H, Iwata, H, Kondo, N, Hartman, M, Hui, M, Lim, W Y, T-C Iau, P, Sawyer, E, Tomlinson, I, Kerin, M, Miller, N, Kang, D, Choi, J-Y, Park, S K, Noh, D-Y, Hopper, J L, Schmidt, D F, Makalic, E, Southey, M C, Teo, S H, Yip, C H, Sivanandan, K, Tay, W-T, Brauch, H, Brüning, T, Hamann, U, Dunning, A M, Shah, M, Andrulis, I L, Knight, J A, Glendon, G, Tchatchou, S, Schmidt, M K, Broeks, A, Rosenberg, E H, van't Veer, L J, Fasching, P A, Renner, S P, Ekici, A B, Beckmann, M W, Shen, C-Y, Hsiung, C-N, Yu, J-C, Hou, M-F, Blot, W, Cai, Q, Wu, A H, Tseng, C-C, Van Den Berg, D, Stram, D O, Cox, A, Brock, I W, Reed, M W R, Muir, K, Lophatananon, A, Stewart-Brown, S, Siriwanarangsan, P, Zheng, W, Deming-Halverson, S, Shrubsole, M J, Long, J, Shu, X-O, Lu, W, Gao, Y-T, Zhang, B, Radice, P, Peterlongo, P, Manoukian, S, Mariette, F, Sangrajrang, S, McKay, J, Couch, F J, Toland, A E, Yannoukakos, D, Fletcher, O, Johnson, N, Silva, I dos Santos, Peto, J, Marme, F, Burwinkel, B, Guénel, P, Truong, T, Sanchez, M, Mulot, C, Bojesen, S E, Nordestgaard, B G, Flyer, H, Brenner, H, Dieffenbach, A K, Arndt, V, Stegmaier, C, Mannermaa, A, Kataja, V, Kosma, V-M, Hartikainen, J M, Lambrechts, D, Yesilyurt, B T, Floris, G, Leunen, K, Chang-Claude, J, Rudolph, A, Seibold, P, Flesch-Janys, D, Wang, X, Olson, J E, Vachon, C, Purrington, K, Giles, G G, Severi, G, Baglietto, L, Haiman, C A, Henderson, B E, Schumacher, F, Le Marchand, L, Simard, J, Dumont, M, Goldberg, M S, Labrèche, F, Winqvist, R, Pylkäs, K, Jukkola-Vuorinen, A, Grip, M, Devilee, P, Tollenaar, R A E M, Seynaeve, C, García-Closas, M, Chanock, S J, Lissowska, J, Figueroa, J D, Czene, K, Eriksson, M, Humphreys, K, Darabi, H, Hooning, M J, Kriege, M, Collée, J M, Tilanus-Linthorst, M, Li, J, Jakubowska, A, Lubinski, J, Jaworska-Bieniek, K, Durda, K, Nevanlinna, H, Muranen, T A, Aittomäki, K, Blomqvist, C, Bogdanova, N, Dörk, T, Hall, P, Chenevix-Trench, G, Easton, D F, Pharoah, P D P, Arias-Perez, J I, Zamora, P, Benítez, J, Milne, R L
Published 2014