Design and Synthesis of Systemically Active Metabotropic Glutamate Subtype-2 and -3 (mGlu2/3) Receptor Positive Allosteric Modulators (PAMs): Pharmacological Characterization and A...

by Dhanya, Raveendra-Panickar, Sheffler, Douglas J., Dahl, Russell, Davis, Melinda, Lee, Pooi San, Yang, Li, Nickols, Hilary Highfield, Cho, Hyekyung P., Smith, Layton H., D’Souza, Manoranjan S., Conn, P. Jeffrey, Der-Avakian, Andre, Markou, Athina, Cosford, Nicholas D. P.
Published 2014

Identification of Inhibitors of NOD1-Induced Nuclear Factor-κB Activation

by Khan, Pasha M., Correa, Ricardo G., Divlianska, Daniela B., Peddibhotla, Satyamaheshwar, Sessions, E. Hampton, Magnuson, Gavin, Brown, Brock, Suyama, Eigo, Yuan, Hongbin, Mangravita-Novo, Arianna, Vicchiarelli, Michael, Su, Ying, Vasile, Stefan, Smith, Layton H., Diaz, Paul W., Reed, John C., Roth, Gregory P.
Published 2011

APJ ACTS AS A DUAL RECEPTOR IN CARDIAC HYPERTROPHY

by Scimia, Maria Cecilia, Hurtado, Cecilia, Ray, Saugata, Metzler, Scott, Wei, Ke, Wang, Jianming, Woods, Chris E., Purcell, Nicole H., Catalucci, Daniele, Akasaka, Takashi, Bueno, Orlando F., Vlasuk, George P., Kaliman, Perla, Bodmer, Rolf, Smith, Layton H., Ashley, Euan, Mercola, Mark, Brown, Joan Heller, Ruiz-Lozano, Pilar
Published 2012

Development of (E)-2-((1,4-Dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-Amidinophenylbenzamides as Potent Inhibitors of Venezuelan Equine Encephalit...

by Schroeder, Chad E., Yao, Tuanli, Sotsky, Julie, Smith, Robert A., Roy, Sudeshna, Chu, Yong-Kyu, Guo, Haixun, Tower, Nichole A., Noah, James W., McKellip, Sara, Sosa, Melinda, Rasmussen, Lynn, Smith, Layton H., White, E. Lucile, Aubé, Jeffrey, Jonsson, Colleen B., Chung, Donghoon, Golden, Jennifer E.
Published 2014

Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response

by Flaherty, Daniel P., Miller, Justin R., Garshott, Danielle M., Hedrick, Michael, Gosalia, Palak, Li, Yujie, Milewski, Monika, Sugarman, Eliot, Vasile, Stefan, Salaniwal, Sumeet, Su, Ying, Smith, Layton H., Chung, Thomas D. Y., Pinkerton, Anthony B., Aubé, Jeffrey, Callaghan, Michael U., Golden, Jennifer E., Fribley, Andrew M., Kaufman, Randal J.
Published 2014

Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma

by Brun, Sonja N., Markant, Shirley L., Esparza, Lourdes A., Garcia, Guillermina, Terry, David, Huang, Jen-Ming, Pavlyukov, Marat S., Li, Xiao-Nan, Grant, Gerald A., Crawford, John R., Levy, Michael L., Conway, Edward M., Smith, Layton H., Nakano, Ichiro, Berezov, Alan, Greene, Mark I., Wang, Qiang, Wechsler-Reya, Robert J.
Published 2014