Oligonucleotide Therapies: The Past and the Present

by Lundin, Karin E., Gissberg, Olof, Smith, C.I. Edvard
Published 2015

Compensatory signals associated with the activation of human GC 5′ splice sites

by Kralovicova, Jana, Hwang, Gyulin, Asplund, A. Charlotta, Churbanov, Alexander, Smith, C. I. Edvard, Vorechovsky, Igor
Published 2011

Differential Evolutionary Wiring of the Tyrosine Kinase Btk

by Nawaz, Hossain M., Kylsten, Per, Hamada, Noriko, Yamamoto, Daisuke, Smith, C. I. Edvard, Lindvall, Jessica M.
Published 2012

B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing

by Mohammad, Dara K., Ali, Raja H., Turunen, Janne J., Nore, Beston F., Smith, C. I. Edvard
Published 2016

mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration

by Roberts, Thomas C., Blomberg, K. Emelie M., Smith, C.I. Edvard, EL Andaloussi, Samir, Wood, Matthew J.A.
Published 2015

Diagnostics of Primary Immunodeficiency Diseases: A Sequencing Capture Approach

by Moens, Lotte N., Falk-Sörqvist, Elin, Asplund, A. Charlotta, Bernatowska, Ewa, Smith, C. I. Edvard, Nilsson, Mats
Published 2014

Disruption of Higher Order DNA Structures in Friedreich’s Ataxia (GAA)n Repeats by PNA or LNA Targeting

by Bergquist, Helen, Rocha, Cristina S. J., Álvarez-Asencio, Rubén, Nguyen, Chi-Hung, Rutland, Mark. W., Smith, C. I. Edvard, Good, Liam, Nielsen, Peter E., Zain, Rula
Published 2016

Splice-Correction Strategies for Treatment of X-Linked Agammaglobulinemia

by Bestas, Burcu, Turunen, Janne J., Blomberg, K. Emelie M., Wang, Qing, Månsson, Robert, EL Andaloussi, Samir, Berglöf, Anna, Smith, C. I. Edvard
Published 2015

Ischemia-Reperfusion Injury and Pregnancy Initiate Time-Dependent and Robust Signs of Up-Regulation of Cardiac Progenitor Cells

by Genead, Rami, Fischer, Helene, Hussain, Alamdar, Jaksch, Marie, Andersson, Agneta B., Ljung, Karin, Bulatovic, Ivana, Franco-Cereceda, Anders, Elsheikh, Elzafir, Corbascio, Matthias, Smith, C. I. Edvard, Sylvén, Christer, Grinnemo, Karl-Henrik
Published 2012

Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene

by Lundin, Karin E., Hamasy, Abdulrahman, Backe, Paul Hoff, Moens, Lotte N., Falk-Sörqvist, Elin, Elgstøen, Katja B., Mørkrid, Lars, Bjørås, Magnar, Granert, Carl, Norlin, Anna-Carin, Nilsson, Mats, Christensson, Birger, Stenmark, Stephan, Smith, C.I. Edvard
Published 2015

Cells release subpopulations of exosomes with distinct molecular and biological properties

by Willms, Eduard, Johansson, Henrik J., Mäger, Imre, Lee, Yi, Blomberg, K. Emelie M., Sadik, Mariam, Alaarg, Amr, Smith, C.I. Edvard, Lehtiö, Janne, EL Andaloussi, Samir, Wood, Matthew J.A., Vader, Pieter
Published 2016

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration

by Roberts, Thomas C., Johansson, Henrik J., McClorey, Graham, Godfrey, Caroline, Blomberg, K. Emelie M., Coursindel, Thibault, Gait, Michael J., Smith, C.I. Edvard, Lehtiö, Janne, EL Andaloussi, Samir, Wood, Matthew J.A.
Published 2015

Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides

by Järver, Peter, Zaghloul, Eman M., Arzumanov, Andrey A., Saleh, Amer F., McClorey, Graham, Hammond, Suzan M., Hällbrink, Mattias, Langel, Ülo, Smith, C.I. Edvard, Wood, Matthew J.A., Gait, Michael J., EL Andaloussi, Samir
Published 2015

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

by Ezzat, Kariem, EL Andaloussi, Samir, Zaghloul, Eman M., Lehto, Taavi, Lindberg, Staffan, Moreno, Pedro M. D., Viola, Joana R., Magdy, Tarek, Abdo, Rania, Guterstam, Peter, Sillard, Rannar, Hammond, Suzan M., Wood, Matthew J. A., Arzumanov, Andrey A., Gait, Michael J., Smith, C. I. Edvard, Hällbrink, Mattias, Langel, Ülo
Published 2011

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

by Moreno, Pedro M. D., Geny, Sylvain, Pabon, Y. Vladimir, Bergquist, Helen, Zaghloul, Eman M., Rocha, Cristina S. J., Oprea, Iulian I., Bestas, Burcu, Andaloussi, Samir EL, Jørgensen, Per T., Pedersen, Erik B., Lundin, Karin E., Zain, Rula, Wengel, Jesper, Smith, C. I. Edvard
Published 2013

Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

by Geny, Sylvain, Moreno, Pedro M. D., Krzywkowski, Tomasz, Gissberg, Olof, Andersen, Nicolai K., Isse, Abdirisaq J., El-Madani, Amro M., Lou, Chenguang, Pabon, Y. Vladimir, Anderson, Brooke A., Zaghloul, Eman M., Zain, Rula, Hrdlicka, Patrick J., Jørgensen, Per T., Nilsson, Mats, Lundin, Karin E., Pedersen, Erik B., Wengel, Jesper, Smith, C. I. Edvard
Published 2016

Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells

by Månsson-Broberg, Agneta, Rodin, Sergey, Bulatovic, Ivana, Ibarra, Cristián, Löfling, Marie, Genead, Rami, Wärdell, Eva, Felldin, Ulrika, Granath, Carl, Alici, Evren, Le Blanc, Katarina, Smith, C.I. Edvard, Salašová, Alena, Westgren, Magnus, Sundström, Erik, Uhlén, Per, Arenas, Ernest, Sylvén, Christer, Tryggvason, Karl, Corbascio, Matthias, Simonson, Oscar E., Österholm, Cecilia, Grinnemo, Karl-Henrik
Published 2016

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

by EL Andaloussi, Samir, Lehto, Taavi, Mäger, Imre, Rosenthal-Aizman, Katri, Oprea, Iulian I., Simonson, Oscar E., Sork, Helena, Ezzat, Kariem, Copolovici, Dana M., Kurrikoff, Kaido, Viola, Joana R., Zaghloul, Eman M., Sillard, Rannar, Johansson, Henrik J., Said Hassane, Fatouma, Guterstam, Peter, Suhorutšenko, Julia, Moreno, Pedro M. D., Oskolkov, Nikita, Hälldin, Jonas, Tedebark, Ulf, Metspalu, Andres, Lebleu, Bernard, Lehtiö, Janne, Smith, C. I. Edvard, Langel, Ülo
Published 2011