Analysis of BENCHMRK 1 & 2 using PhenoSense® assay for darunavir (DRV/r) resistance and exploration of functional monotherapy with RAL vs DRV

by Rockstroh, J, Eron, J, Cooper, D, Steigbigel, R, Nguyen, BY, Xu, X, Wan, H, Rodgers, A, Miller, M, Leavitt, R, Sklar, P, Teppler, H
Published 2010

A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder

by Sellgren, CM, Kegel, ME, Bergen, SE, Ekman, CJ, Olsson, S, Larsson, M, Vawter, MP, Backlund, L, Sullivan, PF, Sklar, P, Smoller, JW, Magnusson, PKE, Hultman, CM, Walther-Jallow, L, Svensson, CI, Lichtenstein, P, Schalling, M, Engberg, G, Erhardt, S, Landén, M
Published 2013

Polygenic dissection of the bipolar phenotype

by Hamshere, M. L., O’Donovan, M. C., Jones, I. R., Jones, L., Kirov, G., Green, E. K., Moskvina, V., Grozeva, D., Bass, N., McQuillin, A., Gurling, H., St Clair, D., Young, A. H., Ferrier, I. N., Farmer, A., McGuffin, P., Sklar, P., Purcell, S., Holmans, P. A., Owen, M. J., Craddock, N.
Published 2011

Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder

by Lee, P H, Perlis, R H, Jung, J-Y, Byrne, E M, Rueckert, E, Siburian, R, Haddad, S, Mayerfeld, C E, Heath, A C, Pergadia, M L, Madden, P A F, Boomsma, D I, Penninx, B W, Sklar, P, Martin, N G, Wray, N R, Purcell, S M, Smoller, J W
Published 2012

Copy number variation in bipolar disorder

by Green, E K, Rees, E, Walters, J T R, Smith, K-G, Forty, L, Grozeva, D, Moran, J L, Sklar, P, Ripke, S, Chambert, K D, Genovese, G, McCarroll, S A, Jones, I, Jones, L, Owen, M J, O'Donovan, M C, Craddock, N, Kirov, G
Published 2016

A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder

by Sellgren, C M, Kegel, M E, Bergen, S E, Ekman, C J, Olsson, S, Larsson, M, Vawter, M P, Backlund, L, Sullivan, P F, Sklar, P, Smoller, J W, Magnusson, P K E, Hultman, C M, Walther-Jallow, L, Svensson, C I, Lichtenstein, P, Schalling, M, Engberg, G, Erhardt, S, Landén, M
Published 2016

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

by Andreassen, O A, Harbo, H F, Wang, Y, Thompson, W K, Schork, A J, Mattingsdal, M, Zuber, V, Bettella, F, Ripke, S, Kelsoe, J R, Kendler, K S, O'Donovan, M C, Sklar, P, McEvoy, L K, Desikan, R S, Lie, B A, Djurovic, S, Dale, A M
Published 2015

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

by Kirov, G, Pocklington, A J, Holmans, P, Ivanov, D, Ikeda, M, Ruderfer, D, Moran, J, Chambert, K, Toncheva, D, Georgieva, L, Grozeva, D, Fjodorova, M, Wollerton, R, Rees, E, Nikolov, I, van de Lagemaat, L N, Bayés, À, Fernandez, E, Olason, P I, Böttcher, Y, Komiyama, N H, Collins, M O, Choudhary, J, Stefansson, K, Stefansson, H, Grant, S G N, Purcell, S, Sklar, P, O'Donovan, M C, Owen, M J
Published 2012

Evidence that duplications of 22q11.2 protect against schizophrenia

by Rees, E, Kirov, G, Sanders, A, Walters, J T R, Chambert, K D, Shi, J, Szatkiewicz, J, O'Dushlaine, C, Richards, A L, Green, E K, Jones, I, Davies, G, Legge, S E, Moran, J L, Pato, C, Pato, M, Genovese, G, Levinson, D, Duan, J, Moy, W, Göring, H H H, Morris, D, Cormican, P, Kendler, K S, O'Neill, F A, Riley, B, Gill, M, Corvin, A, Craddock, N, Sklar, P, Hultman, C, Sullivan, P F, Gejman, P V, McCarroll, S A, O'Donovan, M C, Owen, M J
Published 2014

Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia

by Rees, E, Kirov, G, Walters, J T, Richards, A L, Howrigan, D, Kavanagh, D H, Pocklington, A J, Fromer, M, Ruderfer, D M, Georgieva, L, Carrera, N, Gormley, P, Palta, P, Williams, H, Dwyer, S, Johnson, J S, Roussos, P, Barker, D D, Banks, E, Milanova, V, Rose, S A, Chambert, K, Mahajan, M, Scolnick, E M, Moran, J L, Tsuang, M T, Glatt, S J, Chen, W J, Hwu, H-G, Neale, B M, Palotie, A, Sklar, P, Purcell, S M, McCarroll, S A, Holmans, P, Owen, M J, O'Donovan, M C
Published 2015

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

by Song, J, Bergen, S E, Di Florio, A, Karlsson, R, Charney, A, Ruderfer, D M, Stahl, E A, Chambert, K D, Moran, J L, Gordon-Smith, K, Forty, L, Green, E K, Jones, I, Jones, L, Scolnick, E M, Sklar, P, Smoller, J W, Lichtenstein, P, Hultman, C, Craddock, N, Landén, M, Smoller, Jordan W, Perlis, Roy H, Lee, Phil Hyoun, Castro, Victor M, Hoffnagle, Alison G, Sklar, Pamela, Stahl, Eli A, Purcell, Shaun M, Ruderfer, Douglas M, Charney, Alexander W, Roussos, Panos, Michele Pato, Carlos Pato, Medeiros, Helen, Sobel, Janet, Craddock, Nick, Jones, Ian, Forty, Liz, Florio, Arianna Di, Green, Elaine, Jones, Lisa, Gordon-Smith, Katherine, Landen, Mikael, Hultman, Christina, Jureus, Anders, Bergen, Sarah, McCarroll, Steven, Moran, Jennifer, Smoller, Jordan W, Chambert, Kimberly, Belliveau, Richard A
Published 2016