Mouse models of intestinal cancer

by Jackstadt, Rene, Sansom, Owen J
Published 2015

Colon contradictions: NF-κB signaling in intestinal tumorigenesis

by Fordham, Robert P., Sansom, Owen J.
Published 2015

Exploring molecular genetics of bladder cancer: lessons learned from mouse models

by Ahmad, Imran, Sansom, Owen J., Leung, Hing Y.
Published 2012

FAK Deletion Promotes p53-Mediated Induction of p21, DNA-Damage Responses and Radio-Resistance in Advanced Squamous Cancer Cells

by Graham, Kathryn, Moran-Jones, Kim, Sansom, Owen J., Brunton, Valerie G., Frame, Margaret C.
Published 2011

Inducible progenitor-derived Wingless regulates adult midgut regeneration in Drosophila

by Cordero, Julia B, Stefanatos, Rhoda K, Scopelliti, Alessandro, Vidal, Marcos, Sansom, Owen J
Published 2012

Rac1 drives intestinal stem cell proliferation and regeneration

by Myant, Kevin B, Scopelliti, Alessandro, Haque, Sara, Vidal, Marcos, Sansom, Owen J, Cordero, Julia B
Published 2013

Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis

by Gao, Yang, Vincent, David F., Davis, Anna Jane, Sansom, Owen J., Bartholin, Laurent, Li, Qinglei
Published 2016

Functional exploration of colorectal cancer genomes using Drosophila

by Bangi, Erdem, Murgia, Claudio, Teague, Alexander G.S., Sansom, Owen J., Cagan, Ross L.
Published 2016

GEMMs as preclinical models for testing pancreatic cancer therapies

by Gopinathan, Aarthi, Morton, Jennifer P., Jodrell, Duncan I., Sansom, Owen J.
Published 2015

Apc and p53 interaction in DNA damage and genomic instability in hepatocytes

by Méniel, Valérie, Megges, Matthias, Young, Madeleine A, Cole, Alicia, Sansom, Owen J, Clarke, Alan R
Published 2014

PPARδ status and mismatch repair mediated neoplasia in the mouse intestine

by Reed, Karen R, Sansom, Owen J, Hayes, Anthony J, Gescher, Andreas J, Peters, Jeffrey M, Clarke, Alan R
Published 2006

Local Control of Intestinal Stem Cell Homeostasis by Enteroendocrine Cells in the Adult Drosophila Midgut

by Scopelliti, Alessandro, Cordero, Julia B., Diao, Fengqiu, Strathdee, Karen, White, Benjamin H., Sansom, Owen J., Vidal, Marcos
Published 2014

A Rac1-Independent Role for P-Rex1 in Melanoblasts

by Lindsay, Colin R, Li, Ang, Faller, William, Ozanne, Brad, Welch, Heidi, Machesky, Laura M, Sansom, Owen J
Published 2015

K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder

by Ahmad, Imran, Singh, Lukram Babloo, Foth, Mona, Morris, Carol-Ann, Taketo, Makoto Mark, Wu, Xue-Ru, Leung, Hing Y., Sansom, Owen J., Iwata, Tomoko
Published 2011

p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

by Cole, Alicia M, Ridgway, Rachel A, Derkits, Sahra E, Parry, Lee, Barker, Nick, Clevers, Hans, Clarke, Alan R, Sansom, Owen J
Published 2010

TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis

by Cheung, Eric C., Athineos, Dimitris, Lee, Pearl, Ridgway, Rachel A., Lambie, Wendy, Nixon, Colin, Strathdee, Douglas, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Published 2013

Activated Mutant NRasQ61K Drives Aberrant Melanocyte Signaling, Survival, and Invasiveness via a Rac1-Dependent Mechanism

by Li, Ang, Ma, Yafeng, Jin, Meng, Mason, Susan, Mort, Richard L, Blyth, Karen, Larue, Lionel, Sansom, Owen J, Machesky, Laura M
Published 2012

Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation

by Ma, Yafeng, Li, Ang, Faller, William J., Libertini, Silvana, Fiorito, Florencia, Gillespie, David A., Sansom, Owen J., Yamashiro, Shigeko, Machesky, Laura M.
Published 2013

The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma

by Birch, Joanna, Clarke, Cassie J., Campbell, Andrew D., Campbell, Kirsteen, Mitchell, Louise, Liko, Dritan, Kalna, Gabriela, Strathdee, Douglas, Sansom, Owen J., Neilson, Matthew, Blyth, Karen, Norman, Jim C.
Published 2016

c-Src drives intestinal regeneration and transformation

by Cordero, Julia B, Ridgway, Rachel A, Valeri, Nicola, Nixon, Colin, Frame, Margaret C, Muller, William J, Vidal, Marcos, Sansom, Owen J
Published 2014