The choice of first-line Chronic Myelogenous Leukemia treatment

by Fava, Carmen, Rege-Cambrin, Giovanna, Saglio, Giuseppe
Published 2015

Milestones and Monitoring

by Morotti, Alessandro, Fava, Carmen, Saglio, Giuseppe
Published 2015

Suboptimal Responses in Chronic Myeloid Leukemia

by Jabbour, Elias, Saglio, Giuseppe, Hughes, Timothy P, Kantarjian, Hagop
Published 2012

The targetable role of herpes virus-associated ubiquitin-specific protease (HAUSP) in p190 BCR-ABL leukemia

by Carrà, Giovanna, Panuzzo, Cristina, Crivellaro, Sabrina, Morena, Deborah, Taulli, Riccardo, Guerrasio, Angelo, Saglio, Giuseppe, Morotti, Alessandro
Published 2016

Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex

by Carrà, Giovanna, Crivellaro, Sabrina, Taulli, Riccardo, Guerrasio, Angelo, Saglio, Giuseppe, Morotti, Alessandro
Published 2016

The non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phase

by Crivellaro, Sabrina, Carrà, Giovanna, Panuzzo, Cristina, Taulli, Riccardo, Guerrasio, Angelo, Saglio, Giuseppe, Morotti, Alessandro
Published 2016

The Role of PTEN in Myeloid Malignancies

by Morotti, Alessandro, Panuzzo, Cristina, Crivellaro, Sabrina, Carrà, Giovanna, Torti, Davide, Guerrasio, Angelo, Saglio, Giuseppe
Published 2015

Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias

by Morotti, Alessandro, Carrà, Giovanna, Panuzzo, Cristina, Crivellaro, Sabrina, Taulli, Riccardo, Guerrasio, Angelo, Saglio, Giuseppe
Published 2015

BCR-ABL Promotes PTEN Downregulation in Chronic Myeloid Leukemia

by Panuzzo, Cristina, Crivellaro, Sabrina, Carrà, Giovanna, Guerrasio, Angelo, Saglio, Giuseppe, Morotti, Alessandro
Published 2014

Design and application of a novel PNA probe for the detection at single cell level of JAK2V617F mutation in Myeloproliferative Neoplasms

by Bracco, Enrico, Rosso, Valentina, Serra, Anna, Carnuccio, Francesca, Gaidano, Valentina, Nicoli, Paolo, Musto, Pellegrino, Saglio, Giuseppe, Frassoni, Francesco, Cilloni, Daniela
Published 2013

mTOR pathway activation in multiple myeloma cell lines and primary tumour cells: pomalidomide enhances cytoplasmic-nuclear shuttling of mTOR protein

by Guglielmelli, Tommasina, Giugliano, Emilia, Brunetto, Vanessa, Rapa, Ida, Cappia, Susanna, Giorcelli, Jessica, Rrodhe, Sokol, Papotti, Mauro, Saglio, Giuseppe
Published 2015

Transferrin Receptor 2 Dependent Alterations of Brain Iron Metabolism Affect Anxiety Circuits in the Mouse

by Pellegrino, Rosa Maria, Boda, Enrica, Montarolo, Francesca, Boero, Martina, Mezzanotte, Mariarosa, Saglio, Giuseppe, Buffo, Annalisa, Roetto, Antonella
Published 2016

Characterization of human mitochondrial ferritin promoter: identification of transcription factors and evidences of epigenetic control

by Guaraldo, Michela, Santambrogio, Paolo, Rovelli, Elisabetta, Di Savino, Augusta, Saglio, Giuseppe, Cittaro, Davide, Roetto, Antonella, Levi, Sonia
Published 2016

Dasatinib in imatinib‐resistant or ‐intolerant chronic‐phase, chronic myeloid leukemia patients: 7‐year follow‐up of study CA180‐034

by Shah, Neil P., Rousselot, Philippe, Schiffer, Charles, Rea, Delphine, Cortes, Jorge E., Milone, Jorge, Mohamed, Hesham, Healey, Diane, Kantarjian, Hagop, Hochhaus, Andreas, Saglio, Giuseppe
Published 2016

Lymphocytosis after treatment with dasatinib in chronic myeloid leukemia: Effects on response and toxicity

by Schiffer, Charles A., Cortes, Jorge E., Hochhaus, Andreas, Saglio, Giuseppe, le Coutre, Philipp, Porkka, Kimmo, Mustjoki, Satu, Mohamed, Hesham, Shah, Neil P.
Published 2016

The Wilms’ tumor (WT1) gene expression correlates with the International Prognostic Scoring System (IPSS) score in patients with myelofibrosis and it is a marker of response to the...

by Gallo, Daniela, Nicoli, Paolo, Calabrese, Chiara, Gaidano, Valentina, Petiti, Jessica, Rosso, Valentina, Signorino, Elisabetta, Carturan, Sonia, Bot‐Sartor, Giada, Volpe, Gisella, Frassoni, Francesco, Saglio, Giuseppe, Cilloni, Daniela
Published 2016

Rapid initial decline in BCR-ABL1 is associated with superior responses to second-line nilotinib in patients with chronic-phase chronic myeloid leukemia

by Stein, Andrew M, Martinelli, Giovanni, Hughes, Timothy P, Müller, Martin C, Beppu, Lan, Gottardi, Enrico, Branford, Susan, Soverini, Simona, Woodman, Richard C, Hochhaus, Andreas, Kim, Dong-Wook, Saglio, Giuseppe, Radich, Jerald P
Published 2013

In chronic myeloid leukemia patients on second-line tyrosine kinase inhibitor therapy, deep sequencing of BCR-ABL1 at the time of warning may allow sensitive detection of emerging...

by Soverini, Simona, De Benedittis, Caterina, Castagnetti, Fausto, Gugliotta, Gabriele, Mancini, Manuela, Bavaro, Luana, Machova Polakova, Katerina, Linhartova, Jana, Iurlo, Alessandra, Russo, Domenico, Pane, Fabrizio, Saglio, Giuseppe, Rosti, Gianantonio, Cavo, Michele, Baccarani, Michele, Martinelli, Giovanni
Published 2016

Development of cellular and humoral response against WT1 protein vaccination in mice

by Nicoli, Paolo, Calabrese, Chiara, Pellegrino, Rosa Maria, Rosso, Valentina, Bracco, Enrico, Signorino, Elisabetta, Carturan, Sonia, Petiti, Jessica, Gallo, Daniela, Gaidano, Valentina, De Gobbi, Marco, Roetto, Antonella, Saglio, Giuseppe, Cilloni, Daniela
Published 2015

New alternative splicing BCR/ABL-OOF shows an oncogenic role by lack of inhibition of BCR GTPase activity and an increased of persistence of Rac activation in chronic myeloid leuke...

by Panuzzo, Cristina, Volpe, Gisella, Rocchietti, Elisa Cibrario, Casnici, Claudia, Crotta, Katia, Crivellaro, Sabrina, Carrà, Giovanna, Lorenzatti, Roberta, Peracino, Barbara, Torti, Davide, Morotti, Alessandro, Camacho-Leal, Maria Pilar, Defilippi, Paola, Marelli, Ornella, Saglio, Giuseppe
Published 2015