Local immunotherapy based on agonistic CD40 antibodies effectively inhibits experimental bladder cancer

by Sandin, Linda C, Tötterman, Thomas H, Mangsbo, Sara M
Published 2014

Kick-starting the cancer-immunity cycle by targeting CD40

by Ellmark, P, Mangsbo, S M, Furebring, C, Tötterman, T H, Norlén, P
Published 2015

Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo

by Sandin, Linda C, Eriksson, Fredrik, Ellmark, Peter, Loskog, Angelica SI, Tötterman, Thomas H, Mangsbo, Sara M
Published 2014

Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients

by A. Schiza, J. Wenthe, S. Mangsbo, E. Eriksson, Anders Nilsson, T. H. Tötterman, A. Loskog, G. Ullenhag
Published 2017-04-01

Pre-clinical development of the human CD40 agonistic antibody ADC-1013

by Norlén, Per, Veitonmäki, Niina, Smith, Karin Enell, Tötterman, Thomas H, Mangsbo, Sara M, Furebring, Christina, Ellmark, Peter
Published 2015

ADC-1013, an agonistic CD40 antibody optimized for local immunotherapy of cancer

by Mangsbo, Sara M, Broos, Sissela, Gustafsson, Erika, Furebring, Christina, Veitonmäki, Niina, Dahlen, Eva, Norlen, Per, Lindstedt, Malin, Tötterman, Thomas, Ellmark, Peter
Published 2013

Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients

by Loskog, Angelica, Maleka, Aglaia, Mangsbo, Sara, Svensson, Emma, Lundberg, Christina, Nilsson, Anders, Krause, Johan, Agnarsdóttir, Margrét, Sundin, Anders, Ahlström, Håkan, Tötterman, Thomas H, Ullenhag, Gustav
Published 2016

The human CD40 agonistic antibody ADC-1013 generates immune mediated anti-tumor effects in syngeneic tumor models in hCD40 transgenic mice

by Mangsbo, Sara M, Veitonmäki, Niina, Gustfson, Erika, Smith, Karin Enell, Furebring, Christina, Norlén, Per, Lindstedt, Malin, Tötterman, Thomas H, Ellmark, Peter
Published 2014

Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64+ cells

by Vogel, Stephanie, Grabski, Elena, Buschjäger, Daniela, Klawonn, Frank, Döring, Marius, Wang, Junxi, Fletcher, Erika, Bechmann, Ingo, Witte, Torsten, Durisin, Martin, Schraven, Burkhart, Mangsbo, Sara M., Schönfeld, Kurt, Czeloth, Niklas, Kalinke, Ulrich
Published 2015