Insulin Secretion: A High-affinity Ca2+ Sensor After All?

by Barg, Sebastian, Rorsman, Patrik
Published 2004

Oscillations, Intercellular Coupling, and Insulin Secretion in Pancreatic β Cells

by MacDonald, Patrick E, Rorsman, Patrik
Published 2006

Regulation of calcium in pancreatic α- and β-cells in health and disease

by Rorsman, Patrik, Braun, Matthias, Zhang, Quan
Published 2012

Glucagon secretion from pancreatic α-cells

by Briant, Linford, Salehi, Albert, Vergari, Elisa, Zhang, Quan, Rorsman, Patrik
Published 2016

Corelease and Differential Exit via the Fusion Pore of GABA, Serotonin, and ATP from LDCV in Rat Pancreatic β Cells

by Braun, Matthias, Wendt, Anna, Karanauskaite, Jovita, Galvanovskis, Juris, Clark, Anne, MacDonald, Patrick E., Rorsman, Patrik
Published 2007

Adrenaline Stimulates Glucagon Secretion in Pancreatic A-Cells by Increasing the Ca2+ Current and the Number of Granules Close to the L-Type Ca2+ Channels

by Gromada, Jesper, Bokvist, Krister, Ding, Wei-Guang, Barg, Sebastian, Buschard, Karsten, Renström, Erik, Rorsman, Patrik
Published 1997

Activation of Ca2+-Dependent K+ Channels Contributes to Rhythmic Firing of Action Potentials in Mouse Pancreatic β Cells

by Göpel, Sven O., Kanno, Takahiro, Barg, Sebastian, Eliasson, Lena, Galvanovskis, Juris, Renström, Erik, Rorsman, Patrik
Published 1999

The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells

by Salehi, Albert, Gunnerud, Ulrika, Muhammed, Sarheed J, Östman, Elin, Holst, Jens J, Björck, Inger, Rorsman, Patrik
Published 2012

The two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca2+ dynamics and insulin secretion

by Cane, Matthew C., Parrington, John, Rorsman, Patrik, Galione, Antony, Rutter, Guy A.
Published 2016

Regulated Exocytosis of GABA-containing Synaptic-like Microvesicles in Pancreatic β-cells

by Braun, Matthias, Wendt, Anna, Birnir, Bryndis, Broman, Jonas, Eliasson, Lena, Galvanovskis, Juris, Gromada, Jesper, Mulder, Hindrik, Rorsman, Patrik
Published 2004

A KATP Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans

by MacDonald, Patrick E, Marinis, Yang Zhang De, Ramracheya, Reshma, Salehi, Albert, Ma, Xiaosong, Johnson, Paul R. V, Cox, Roger, Eliasson, Lena, Rorsman, Patrik
Published 2007

SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells

by Eliasson, Lena, Ma, Xiaosong, Renström, Erik, Barg, Sebastian, Berggren, Per-Olof, Galvanovskis, Juris, Gromada, Jesper, Jing, Xingjun, Lundquist, Ingmar, Salehi, Albert, Sewing, Sabine, Rorsman, Patrik
Published 2003

PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery

by Ramracheya, Reshma D., McCulloch, Laura J., Clark, Anne, Wiggins, David, Johannessen, Helene, Olsen, Magnus Kringstad, Cai, Xing, Zhao, Chun-Mei, Chen, Duan, Rorsman, Patrik
Published 2016

High-content screening identifies a role for Na+ channels in insulin production

by Szabat, Marta, Modi, Honey, Ramracheya, Reshma, Girbinger, Vroni, Chan, Forson, Lee, Jason T. C., Piske, Micah, Kamal, Sepehr, Carol Yang, Yu Hsuan, Welling, Andrea, Rorsman, Patrik, Johnson, James D.
Published 2015

Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells

by Brereton, Melissa F., Rohm, Maria, Shimomura, Kenju, Holland, Christian, Tornovsky-Babeay, Sharona, Dadon, Daniela, Iberl, Michaela, Chibalina, Margarita V., Lee, Sheena, Glaser, Benjamin, Dor, Yuval, Rorsman, Patrik, Clark, Anne, Ashcroft, Frances M.
Published 2016

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression

by Zhang, Quan, Chibalina, Margarita V, Bengtsson, Martin, Groschner, Lukas N, Ramracheya, Reshma, Rorsman, Nils J G, Leiss, Veronika, Nassar, Mohammed A, Welling, Andrea, Gribble, Fiona M, Reimann, Frank, Hofmann, Franz, Wood, John N, Ashcroft, Frances M, Rorsman, Patrik
Published 2014

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

by Brereton, Melissa F., Iberl, Michaela, Shimomura, Kenju, Zhang, Quan, Adriaenssens, Alice E., Proks, Peter, Spiliotis, Ioannis I., Dace, William, Mattis, Katia K., Ramracheya, Reshma, Gribble, Fiona M., Reimann, Frank, Clark, Anne, Rorsman, Patrik, Ashcroft, Frances M.
Published 2014

Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes

by Rosengren, Anders H., Braun, Matthias, Mahdi, Taman, Andersson, Sofia A., Travers, Mary E., Shigeto, Makoto, Zhang, Enming, Almgren, Peter, Ladenvall, Claes, Axelsson, Annika S., Edlund, Anna, Pedersen, Morten Gram, Jonsson, Anna, Ramracheya, Reshma, Tang, Yunzhao, Walker, Jonathan N., Barrett, Amy, Johnson, Paul R.V., Lyssenko, Valeriya, McCarthy, Mark I., Groop, Leif, Salehi, Albert, Gloyn, Anna L., Renström, Erik, Rorsman, Patrik, Eliasson, Lena
Published 2012

Role of KATP Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

by Zhang, Quan, Ramracheya, Reshma, Lahmann, Carolina, Tarasov, Andrei, Bengtsson, Martin, Braha, Orit, Braun, Matthias, Brereton, Melissa, Collins, Stephan, Galvanovskis, Juris, Gonzalez, Alejandro, Groschner, Lukas N., Rorsman, Nils J.G., Salehi, Albert, Travers, Mary E., Walker, Jonathan N., Gloyn, Anna L., Gribble, Fiona, Johnson, Paul R.V., Reimann, Frank, Ashcroft, Frances M., Rorsman, Patrik
Published 2013

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

by Gheni, Ghupurjan, Ogura, Masahito, Iwasaki, Masahiro, Yokoi, Norihide, Minami, Kohtaro, Nakayama, Yasumune, Harada, Kazuo, Hastoy, Benoit, Wu, Xichen, Takahashi, Harumi, Kimura, Kazushi, Matsubara, Toshiya, Hoshikawa, Ritsuko, Hatano, Naoya, Sugawara, Kenji, Shibasaki, Tadao, Inagaki, Nobuya, Bamba, Takeshi, Mizoguchi, Akira, Fukusaki, Eiichiro, Rorsman, Patrik, Seino, Susumu
Published 2014